KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EHMT1
All Species:
15.15
Human Site:
Y235
Identified Species:
41.67
UniProt:
Q9H9B1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9B1
NP_001138999.1
1267
138254
Y235
S
L
P
Q
N
Q
C
Y
M
A
T
T
K
S
Q
Chimpanzee
Pan troglodytes
XP_520395
1499
164011
Y467
S
L
P
Q
N
Q
C
Y
M
A
T
T
K
S
Q
Rhesus Macaque
Macaca mulatta
XP_001117637
1311
143552
K235
S
S
E
S
S
L
K
K
K
F
L
K
R
K
G
Dog
Lupus familis
XP_848228
1265
138176
Y234
S
L
P
Q
N
Q
C
Y
M
A
T
T
K
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z148
1263
138021
S221
A
T
A
G
P
E
P
S
P
A
T
T
A
A
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509394
1282
141003
Y235
S
L
P
Q
N
Q
G
Y
V
A
T
A
K
S
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396833
1265
141508
R268
T
V
P
V
T
R
K
R
R
T
G
R
P
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785941
548
61937
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82175
794
88134
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
80.8
89.7
N.A.
45.5
N.A.
N.A.
78
N.A.
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
24.7
Protein Similarity:
100
78.7
81.8
94.1
N.A.
60.8
N.A.
N.A.
85.5
N.A.
N.A.
N.A.
N.A.
N.A.
51.5
N.A.
33.8
P-Site Identity:
100
100
6.6
100
N.A.
26.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
46.6
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
0
0
56
0
12
12
12
0
% A
% Cys:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
12
0
0
0
12
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
23
12
12
0
0
12
45
12
0
% K
% Leu:
0
45
0
0
0
12
0
0
0
0
12
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
56
0
12
0
12
0
12
0
0
0
12
0
0
% P
% Gln:
0
0
0
45
0
45
0
0
0
0
0
0
0
0
56
% Q
% Arg:
0
0
0
0
0
12
0
12
12
0
0
12
12
12
0
% R
% Ser:
56
12
0
12
12
0
0
12
0
0
0
0
0
45
0
% S
% Thr:
12
12
0
0
12
0
0
0
0
12
56
45
0
0
0
% T
% Val:
0
12
0
12
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _