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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM45 All Species: 20.91
Human Site: S491 Identified Species: 76.67
UniProt: Q9H8W5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8W5 NP_079464.2 580 64359 S491 K E Q H V Q G S P F T V M V R
Chimpanzee Pan troglodytes XP_001145514 580 64336 S491 K E Q H V Q G S P F T V T V R
Rhesus Macaque Macaca mulatta XP_001113153 580 64211 S491 K E Q H V Q G S P F T V T V R
Dog Lupus familis XP_533020 580 63668 S491 K E Q H V Q G S P F T V T V R
Cat Felis silvestris
Mouse Mus musculus Q6PFY8 580 64167 S491 R E Q H V Q G S P F N V T V R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609193 921 101527 T832 A Q G T L I L T I T I N D R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796095 618 67889 S484 N G H H I R G S P F S V S V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 96.5 91.3 N.A. 85.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 22.9 N.A. N.A. 33.8
Protein Similarity: 100 98.9 98 94.6 N.A. 92.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 35.9 N.A. N.A. 54.2
P-Site Identity: 100 93.3 93.3 93.3 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A. 46.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % D
% Glu: 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 % F
% Gly: 0 15 15 0 0 0 86 0 0 0 0 0 0 0 0 % G
% His: 0 0 15 86 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 15 0 0 15 0 15 0 0 0 0 % I
% Lys: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 0 0 0 15 0 15 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 15 0 0 0 0 0 0 0 0 0 15 15 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 86 0 0 0 0 0 15 % P
% Gln: 0 15 72 0 0 72 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 0 15 0 0 0 0 0 0 0 15 72 % R
% Ser: 0 0 0 0 0 0 0 86 0 0 15 0 15 0 0 % S
% Thr: 0 0 0 15 0 0 0 15 0 15 58 0 58 0 0 % T
% Val: 0 0 0 0 72 0 0 0 0 0 0 86 0 86 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _