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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM188A
All Species:
38.48
Human Site:
Y343
Identified Species:
76.97
UniProt:
Q9H8M7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8M7
NP_079224.1
445
49725
Y343
D
L
V
S
D
P
E
Y
I
N
L
M
K
N
K
Chimpanzee
Pan troglodytes
XP_001149628
445
49688
Y343
D
L
V
S
D
P
E
Y
I
N
L
M
K
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544246
480
53561
Y378
D
L
V
S
D
P
E
Y
I
N
L
M
K
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CV28
444
49594
Y342
D
L
V
S
D
P
E
Y
I
N
L
M
K
N
K
Rat
Rattus norvegicus
NP_001099592
444
49484
Y342
D
L
V
S
D
P
E
Y
I
N
L
M
K
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508622
447
50159
Y345
D
L
V
S
D
P
E
Y
V
N
L
M
K
T
K
Chicken
Gallus gallus
XP_418629
445
50220
Y343
D
L
V
S
D
P
E
Y
V
N
L
M
K
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0AUR5
446
50092
Y344
D
L
V
S
E
P
D
Y
V
N
L
M
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWN5
560
61736
Y459
N
L
V
S
E
P
A
Y
V
A
L
M
Q
K
R
Honey Bee
Apis mellifera
XP_396280
433
49407
Y332
G
L
V
T
D
S
D
Y
V
N
V
M
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197555
419
47074
K328
T
Q
R
L
D
P
E
K
C
G
I
V
L
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001145800
620
67621
F474
L
R
D
T
D
I
N
F
P
S
D
K
L
E
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87
N.A.
95.7
95
N.A.
88.1
86.9
N.A.
73.9
N.A.
38
35.9
N.A.
43.6
Protein Similarity:
100
100
N.A.
90
N.A.
97.7
97.9
N.A.
93.5
93
N.A.
86.7
N.A.
53.3
56.6
N.A.
63.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
73.3
N.A.
46.6
53.3
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
80
80
N.A.
33.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
67
0
9
0
84
0
17
0
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
17
0
67
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
42
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
9
75
17
75
% K
% Leu:
9
84
0
9
0
0
0
0
0
0
75
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
75
0
0
0
42
9
% N
% Pro:
0
0
0
0
0
84
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
75
0
9
0
0
0
9
0
0
0
9
0
% S
% Thr:
9
0
0
17
0
0
0
0
0
0
0
0
0
17
0
% T
% Val:
0
0
84
0
0
0
0
0
42
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _