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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM188A
All Species:
28.48
Human Site:
S374
Identified Species:
56.97
UniProt:
Q9H8M7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8M7
NP_079224.1
445
49725
S374
E
F
F
P
D
Q
G
S
S
G
P
E
S
F
T
Chimpanzee
Pan troglodytes
XP_001149628
445
49688
S374
E
F
F
P
D
Q
G
S
S
G
P
E
S
F
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544246
480
53561
S409
E
F
F
P
D
Q
G
S
S
G
P
E
S
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CV28
444
49594
S373
E
F
F
P
D
Q
G
S
S
G
P
E
S
F
T
Rat
Rattus norvegicus
NP_001099592
444
49484
S373
E
F
F
P
D
Q
G
S
S
G
P
E
S
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508622
447
50159
S376
E
F
F
P
E
Q
D
S
R
V
P
E
S
F
T
Chicken
Gallus gallus
XP_418629
445
50220
S374
E
F
F
P
E
Q
D
S
R
V
S
E
S
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0AUR5
446
50092
S375
E
F
F
P
D
Q
D
S
V
I
P
D
S
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWN5
560
61736
R490
E
F
F
P
L
E
S
R
S
T
P
D
T
F
E
Honey Bee
Apis mellifera
XP_396280
433
49407
R363
E
F
F
P
E
E
P
R
T
C
P
D
T
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197555
419
47074
R348
F
F
P
D
E
P
D
R
L
L
P
E
Y
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001145800
620
67621
L513
G
M
K
D
P
T
G
L
M
G
K
K
Q
F
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87
N.A.
95.7
95
N.A.
88.1
86.9
N.A.
73.9
N.A.
38
35.9
N.A.
43.6
Protein Similarity:
100
100
N.A.
90
N.A.
97.7
97.9
N.A.
93.5
93
N.A.
86.7
N.A.
53.3
56.6
N.A.
63.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
73.3
66.6
N.A.
66.6
N.A.
46.6
40
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
80
73.3
N.A.
73.3
N.A.
66.6
73.3
N.A.
40
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
17
50
0
34
0
0
0
0
25
0
0
0
% D
% Glu:
84
0
0
0
34
17
0
0
0
0
0
67
0
0
9
% E
% Phe:
9
92
84
0
0
0
0
0
0
0
0
0
0
100
0
% F
% Gly:
9
0
0
0
0
0
50
0
0
50
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
9
9
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
84
9
9
9
0
0
0
84
0
0
0
17
% P
% Gln:
0
0
0
0
0
67
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
25
17
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
67
50
0
9
0
67
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
9
9
0
0
17
0
75
% T
% Val:
0
0
0
0
0
0
0
0
9
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _