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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM188A
All Species:
35.76
Human Site:
S274
Identified Species:
71.52
UniProt:
Q9H8M7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8M7
NP_079224.1
445
49725
S274
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Chimpanzee
Pan troglodytes
XP_001149628
445
49688
S274
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544246
480
53561
S309
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CV28
444
49594
S273
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Rat
Rattus norvegicus
NP_001099592
444
49484
S273
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508622
447
50159
S276
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
L
Chicken
Gallus gallus
XP_418629
445
50220
S274
K
V
G
S
Y
L
K
S
P
K
F
P
I
W
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0AUR5
446
50092
S275
K
V
G
A
F
L
K
S
P
K
F
P
I
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWN5
560
61736
N390
T
V
G
S
F
F
K
N
P
R
Y
P
V
W
V
Honey Bee
Apis mellifera
XP_396280
433
49407
S263
E
V
G
T
F
L
K
S
P
S
N
P
I
W
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197555
419
47074
L260
L
I
G
F
L
T
I
L
E
N
L
K
Y
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001145800
620
67621
C405
K
V
G
Q
Y
L
K
C
P
K
W
P
I
W
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87
N.A.
95.7
95
N.A.
88.1
86.9
N.A.
73.9
N.A.
38
35.9
N.A.
43.6
Protein Similarity:
100
100
N.A.
90
N.A.
97.7
97.9
N.A.
93.5
93
N.A.
86.7
N.A.
53.3
56.6
N.A.
63.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
46.6
60
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
9
25
9
0
0
0
0
67
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
84
0
59
% I
% Lys:
75
0
0
0
0
0
92
0
0
75
0
9
0
0
0
% K
% Leu:
9
0
0
0
9
84
0
9
0
0
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
92
0
0
92
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
67
0
0
0
75
0
9
0
0
0
0
0
% S
% Thr:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
92
0
0
0
0
0
0
0
0
0
0
9
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
92
0
% W
% Tyr:
0
0
0
0
67
0
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _