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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC12
All Species:
20.3
Human Site:
S444
Identified Species:
44.67
UniProt:
Q9H892
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H892
NP_060338.3
705
78738
S444
K
T
D
P
K
V
S
S
S
S
A
L
C
Q
C
Chimpanzee
Pan troglodytes
XP_508759
732
81550
S444
K
T
D
P
K
V
S
S
S
S
A
L
C
Q
C
Rhesus Macaque
Macaca mulatta
XP_001084630
705
78442
S444
K
T
D
P
K
V
S
S
S
S
A
L
C
Q
C
Dog
Lupus familis
XP_536570
689
77080
S428
E
R
D
P
M
V
T
S
P
S
A
L
C
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW49
704
78735
S443
N
R
E
P
K
I
T
S
P
S
A
L
C
Q
C
Rat
Rattus norvegicus
NP_001004246
704
78845
S443
K
R
E
P
K
L
T
S
P
S
A
L
C
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521579
596
64809
A361
T
I
R
S
Q
L
A
A
C
P
D
L
W
D
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU95
660
75087
K394
Q
A
V
L
E
L
A
K
I
S
Q
E
L
R
S
Zebra Danio
Brachydanio rerio
XP_692245
1008
111628
D429
L
S
N
T
T
T
A
D
P
K
L
L
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794332
573
63704
R338
I
R
K
E
I
A
S
R
K
E
F
W
E
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12118
346
37200
K111
D
L
K
M
Q
G
N
K
A
M
A
N
K
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
95.1
76.3
N.A.
75
77
N.A.
49.2
N.A.
20.7
26.8
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
94.4
97.8
87.5
N.A.
88.6
89.6
N.A.
62.7
N.A.
41.4
44.8
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
100
60
N.A.
60
66.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
80
86.6
N.A.
33.3
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
28
10
10
0
64
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
55
0
55
% C
% Asp:
10
0
37
0
0
0
0
10
0
0
10
0
0
19
0
% D
% Glu:
10
0
19
10
10
0
0
0
0
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
37
0
19
0
46
0
0
19
10
10
0
0
10
0
0
% K
% Leu:
10
10
0
10
0
28
0
0
0
0
10
73
10
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
55
0
0
0
0
37
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
19
0
0
0
0
0
10
0
0
46
0
% Q
% Arg:
0
37
10
0
0
0
0
10
0
0
0
0
0
19
0
% R
% Ser:
0
10
0
10
0
0
37
55
28
64
0
0
0
10
19
% S
% Thr:
10
28
0
10
10
10
28
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
37
0
0
0
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _