KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1B
All Species:
12.42
Human Site:
S437
Identified Species:
24.85
UniProt:
Q9H816
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H816
NP_073747.1
532
60002
S437
G
F
S
V
H
L
R
S
T
D
E
E
F
I
S
Chimpanzee
Pan troglodytes
XP_524804
532
59965
S437
G
F
S
V
H
L
R
S
T
D
E
E
F
I
S
Rhesus Macaque
Macaca mulatta
XP_001110949
532
60020
S437
G
F
S
V
P
L
R
S
T
D
E
E
F
L
S
Dog
Lupus familis
XP_848274
530
59628
E436
D
E
E
F
L
S
L
E
T
G
E
D
M
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7W7
541
61051
I438
F
S
V
Q
L
Q
P
I
D
E
F
L
F
P
E
Rat
Rattus norvegicus
Q5XIX3
698
78171
I500
F
F
K
R
K
D
E
I
T
D
E
C
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506464
563
63126
S440
V
P
A
T
Q
A
A
S
L
A
F
P
L
K
S
Chicken
Gallus gallus
Q5QJC3
457
50812
S363
L
E
E
Y
I
E
Q
S
D
G
L
G
G
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGE5
639
71693
S478
A
A
A
P
P
P
S
S
T
E
K
P
C
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787553
599
67104
E462
K
F
K
D
L
D
Q
E
P
D
L
E
K
D
T
Poplar Tree
Populus trichocarpa
XP_002332533
360
41193
D266
L
K
P
V
K
G
D
D
N
L
F
G
S
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174061
422
47744
P328
E
F
I
K
L
V
K
P
K
S
M
K
G
I
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.3
81.5
N.A.
76.7
23.9
N.A.
56.3
48.1
N.A.
22.8
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
100
97.1
88.5
N.A.
84.8
39.5
N.A.
67.5
60.1
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
100
86.6
13.3
N.A.
6.6
26.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
20
N.A.
13.3
33.3
N.A.
20
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.5
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
0
0
9
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% C
% Asp:
9
0
0
9
0
17
9
9
17
42
0
9
0
9
0
% D
% Glu:
9
17
17
0
0
9
9
17
0
17
42
34
0
9
9
% E
% Phe:
17
50
0
9
0
0
0
0
0
0
25
0
34
0
0
% F
% Gly:
25
0
0
0
0
9
0
0
0
17
0
17
17
9
0
% G
% His:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
0
17
0
0
0
0
0
25
0
% I
% Lys:
9
9
17
9
17
0
9
0
9
0
9
9
9
9
9
% K
% Leu:
17
0
0
0
34
25
9
0
9
9
17
9
17
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
9
9
9
17
9
9
9
9
0
0
17
0
9
0
% P
% Gln:
0
0
0
9
9
9
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
25
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
25
0
0
9
9
50
0
9
0
0
9
9
34
% S
% Thr:
0
0
0
9
0
0
0
0
50
0
0
0
0
0
17
% T
% Val:
9
0
9
34
0
9
0
0
0
0
0
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _