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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1B All Species: 16.67
Human Site: S331 Identified Species: 33.33
UniProt: Q9H816 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H816 NP_073747.1 532 60002 S331 Q Q Y M S S S S R K P S L L W
Chimpanzee Pan troglodytes XP_524804 532 59965 S331 Q Q Y M S S S S R K P S L L W
Rhesus Macaque Macaca mulatta XP_001110949 532 60020 S331 Q Q Y M S S S S R K P S F L W
Dog Lupus familis XP_848274 530 59628 S330 S V Q Q Y M N S S S R K P S F
Cat Felis silvestris
Mouse Mus musculus Q8C7W7 541 61051 S332 Q Q Y M S S S S R K T N V L W
Rat Rattus norvegicus Q5XIX3 698 78171 D394 E D D D L F D D P L L T H S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506464 563 63126 Q334 Y M R V R R P Q R G Q N V L R
Chicken Gallus gallus Q5QJC3 457 50812 T257 T G R P V K V T H P Q I H L I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGE5 639 71693 P372 R E E I V Y K P L G A L K R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787553 599 67104 S356 P G E V M R P S L R K R Q S I
Poplar Tree Populus trichocarpa XP_002332533 360 41193 Q160 T R E V A A Q Q V V D I I A S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_174061 422 47744 T222 L G F Q D I F T T D T S L T R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.3 81.5 N.A. 76.7 23.9 N.A. 56.3 48.1 N.A. 22.8 N.A. N.A. N.A. N.A. 31.2
Protein Similarity: 100 100 97.1 88.5 N.A. 84.8 39.5 N.A. 67.5 60.1 N.A. 37.8 N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 100 93.3 6.6 N.A. 80 0 N.A. 13.3 6.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 20 N.A. 93.3 13.3 N.A. 33.3 13.3 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 23.5 N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 0 0 0 0 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 9 9 0 9 9 0 9 9 0 0 0 0 % D
% Glu: 9 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 9 9 0 0 0 0 0 9 0 9 % F
% Gly: 0 25 0 0 0 0 0 0 0 17 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 17 0 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 0 17 9 0 17 % I
% Lys: 0 0 0 0 0 9 9 0 0 34 9 9 9 0 0 % K
% Leu: 9 0 0 0 9 0 0 0 17 9 9 9 25 50 0 % L
% Met: 0 9 0 34 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 17 0 0 0 % N
% Pro: 9 0 0 9 0 0 17 9 9 9 25 0 9 0 0 % P
% Gln: 34 34 9 17 0 0 9 17 0 0 17 0 9 0 0 % Q
% Arg: 9 9 17 0 9 17 0 0 42 9 9 9 0 9 25 % R
% Ser: 9 0 0 0 34 34 34 50 9 9 0 34 0 25 9 % S
% Thr: 17 0 0 0 0 0 0 17 9 0 17 9 0 9 9 % T
% Val: 0 9 0 25 17 0 9 0 9 9 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % W
% Tyr: 9 0 34 0 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _