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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1B
All Species:
13.94
Human Site:
S329
Identified Species:
27.88
UniProt:
Q9H816
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H816
NP_073747.1
532
60002
S329
S
V
Q
Q
Y
M
S
S
S
S
R
K
P
S
L
Chimpanzee
Pan troglodytes
XP_524804
532
59965
S329
S
V
Q
Q
Y
M
S
S
S
S
R
K
P
S
L
Rhesus Macaque
Macaca mulatta
XP_001110949
532
60020
S329
S
V
Q
Q
Y
M
S
S
S
S
R
K
P
S
F
Dog
Lupus familis
XP_848274
530
59628
M328
P
N
S
V
Q
Q
Y
M
N
S
S
S
R
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7W7
541
61051
S330
S
V
Q
Q
Y
M
S
S
S
S
R
K
T
N
V
Rat
Rattus norvegicus
Q5XIX3
698
78171
F392
S
E
E
D
D
D
L
F
D
D
P
L
L
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506464
563
63126
R332
Q
R
Y
M
R
V
R
R
P
Q
R
G
Q
N
V
Chicken
Gallus gallus
Q5QJC3
457
50812
K255
L
P
T
G
R
P
V
K
V
T
H
P
Q
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGE5
639
71693
Y370
C
G
R
E
E
I
V
Y
K
P
L
G
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787553
599
67104
R354
S
V
P
G
E
V
M
R
P
S
L
R
K
R
Q
Poplar Tree
Populus trichocarpa
XP_002332533
360
41193
A158
F
P
T
R
E
V
A
A
Q
Q
V
V
D
I
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174061
422
47744
I220
H
L
L
G
F
Q
D
I
F
T
T
D
T
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.3
81.5
N.A.
76.7
23.9
N.A.
56.3
48.1
N.A.
22.8
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
100
97.1
88.5
N.A.
84.8
39.5
N.A.
67.5
60.1
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
100
93.3
6.6
N.A.
80
6.6
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
20
N.A.
26.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.5
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
0
0
0
9
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
9
9
0
9
9
0
9
9
0
0
% D
% Glu:
0
9
9
9
25
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
9
0
0
9
9
0
0
0
0
0
9
% F
% Gly:
0
9
0
25
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% H
% Ile:
0
0
0
0
0
9
0
9
0
0
0
0
0
17
9
% I
% Lys:
0
0
0
0
0
0
0
9
9
0
0
34
9
9
9
% K
% Leu:
9
9
9
0
0
0
9
0
0
0
17
9
9
9
25
% L
% Met:
0
0
0
9
0
34
9
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
9
0
0
0
0
17
0
% N
% Pro:
9
17
9
0
0
9
0
0
17
9
9
9
25
0
9
% P
% Gln:
9
0
34
34
9
17
0
0
9
17
0
0
17
0
9
% Q
% Arg:
0
9
9
9
17
0
9
17
0
0
42
9
9
9
0
% R
% Ser:
50
0
9
0
0
0
34
34
34
50
9
9
0
34
0
% S
% Thr:
0
0
17
0
0
0
0
0
0
17
9
0
17
9
0
% T
% Val:
0
42
0
9
0
25
17
0
9
0
9
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
34
0
9
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _