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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1B
All Species:
31.52
Human Site:
S278
Identified Species:
63.03
UniProt:
Q9H816
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H816
NP_073747.1
532
60002
S278
I
P
Y
S
D
H
S
S
Y
S
E
L
R
A
F
Chimpanzee
Pan troglodytes
XP_524804
532
59965
S278
I
P
Y
S
D
H
S
S
Y
S
E
L
R
A
F
Rhesus Macaque
Macaca mulatta
XP_001110949
532
60020
S278
I
P
Y
S
D
H
S
S
Y
S
E
L
C
A
F
Dog
Lupus familis
XP_848274
530
59628
S278
I
P
Y
S
D
H
S
S
F
S
E
L
Q
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7W7
541
61051
S278
V
P
Y
S
D
H
S
S
Y
S
E
L
R
A
F
Rat
Rattus norvegicus
Q5XIX3
698
78171
S321
A
C
F
S
F
H
S
S
Y
S
E
I
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506464
563
63126
S278
V
P
Y
S
D
H
S
S
F
S
E
L
W
D
F
Chicken
Gallus gallus
Q5QJC3
457
50812
E208
L
E
Q
M
R
L
L
E
L
P
E
V
F
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGE5
639
71693
S321
A
C
F
S
F
H
S
S
Y
L
E
V
K
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787553
599
67104
S282
I
P
Y
S
S
H
S
S
Y
N
E
L
I
R
F
Poplar Tree
Populus trichocarpa
XP_002332533
360
41193
Q111
L
M
Y
T
G
D
F
Q
W
E
V
D
S
K
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174061
422
47744
H173
V
A
D
I
I
A
S
H
P
S
H
D
I
I
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.3
81.5
N.A.
76.7
23.9
N.A.
56.3
48.1
N.A.
22.8
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
100
97.1
88.5
N.A.
84.8
39.5
N.A.
67.5
60.1
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
100
93.3
80
N.A.
93.3
53.3
N.A.
73.3
6.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
73.3
N.A.
86.6
20
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
23.5
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
9
0
0
0
0
0
0
0
34
0
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
0
50
9
0
0
0
0
0
17
0
25
0
% D
% Glu:
0
9
0
0
0
0
0
9
0
9
84
0
0
0
0
% E
% Phe:
0
0
17
0
17
0
9
0
17
0
0
0
9
0
75
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
75
0
9
0
0
9
0
0
0
0
% H
% Ile:
42
0
0
9
9
0
0
0
0
0
0
9
17
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
17
9
0
% K
% Leu:
17
0
0
0
0
9
9
0
9
9
0
59
0
0
0
% L
% Met:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
59
0
0
0
0
0
0
9
9
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
25
9
9
% R
% Ser:
0
0
0
75
9
0
84
75
0
67
0
0
9
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
9
% T
% Val:
25
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% W
% Tyr:
0
0
67
0
0
0
0
0
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _