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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH2D4A All Species: 31.21
Human Site: S20 Identified Species: 98.1
UniProt: Q9H788 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H788 NP_071354.2 454 52727 S20 P D L L A E L S E E Q K Q I L
Chimpanzee Pan troglodytes XP_001148190 454 52742 S20 P D L L A E L S E E Q K Q I L
Rhesus Macaque Macaca mulatta XP_001099045 454 52578 S20 P D L L A E L S E E Q K Q I L
Dog Lupus familis XP_848220 453 51924 S20 P D L L A E L S E E Q K Q I L
Cat Felis silvestris
Mouse Mus musculus Q9D7V1 421 48442 S20 P D L L A E L S E E Q K Q I L
Rat Rattus norvegicus Q6AYC8 422 48504 S20 P D L L A E L S E E Q K Q I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507878 464 53528 S20 P D L L A E L S E E Q K H I L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781629 470 56428 S20 P E L L A E L S E H Q K E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 94.7 84.3 N.A. 73.7 73.5 N.A. 67 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 35.7
Protein Similarity: 100 98.6 97.3 90.5 N.A. 81 81 N.A. 79.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 55.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 13 0 0 0 100 0 0 100 88 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 88 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 0 0 100 100 0 0 100 0 0 0 0 0 0 13 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 100 0 75 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _