KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR55
All Species:
4.55
Human Site:
T378
Identified Species:
9.09
UniProt:
Q9H6Y2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6Y2
NP_060176.2
383
42123
T378
A
Q
E
E
K
E
E
T
G
D
D
S
D
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535212
385
42379
S380
A
K
K
E
E
E
E
S
E
D
D
S
D
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX97
388
42592
E379
A
P
E
E
V
V
R
E
S
D
D
D
D
D
D
Rat
Rattus norvegicus
A1L112
384
42124
E378
A
P
E
E
V
S
G
E
S
D
D
D
S
D
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518168
201
21640
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRF9
387
43154
E375
G
K
E
G
E
N
D
E
D
D
D
D
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T088
498
55303
A492
D
G
D
D
D
P
G
A
G
P
S
N
M
A
_
Honey Bee
Apis mellifera
XP_623745
423
47774
A416
P
S
S
K
I
D
N
A
S
T
F
F
S
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788545
584
64374
R559
Q
K
T
N
V
D
P
R
G
K
A
G
K
N
D
Poplar Tree
Populus trichocarpa
XP_002305841
348
38264
S343
N
A
N
G
A
A
S
S
F
F
A
D
L
_
_
Maize
Zea mays
NP_001132448
357
38978
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565782
353
38407
N347
A
N
T
L
N
A
T
N
N
F
F
A
D
L
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.4
N.A.
87.3
89
N.A.
42
N.A.
N.A.
60.9
N.A.
27.5
29.5
N.A.
25
Protein Similarity:
100
N.A.
N.A.
96.3
N.A.
92.2
93.4
N.A.
47.7
N.A.
N.A.
77
N.A.
42.5
51
N.A.
41.9
P-Site Identity:
100
N.A.
N.A.
61.5
N.A.
40
35.7
N.A.
0
N.A.
N.A.
20
N.A.
7.1
0
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
92.3
N.A.
40
35.7
N.A.
0
N.A.
N.A.
46.6
N.A.
28.5
13.3
N.A.
20
Percent
Protein Identity:
31.5
32.3
N.A.
31
N.A.
N.A.
Protein Similarity:
48.3
48.8
N.A.
48
N.A.
N.A.
P-Site Identity:
0
0
N.A.
14.2
N.A.
N.A.
P-Site Similarity:
7.6
0
N.A.
21.4
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
0
0
9
17
0
17
0
0
17
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
9
17
9
0
9
42
42
34
34
34
17
% D
% Glu:
0
0
34
34
17
17
17
25
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
17
17
9
0
0
0
% F
% Gly:
9
9
0
17
0
0
17
0
25
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
9
9
9
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
9
9
9
9
9
9
9
9
0
0
9
0
9
0
% N
% Pro:
9
17
0
0
0
9
9
0
0
9
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
0
9
9
17
25
0
9
17
17
0
9
% S
% Thr:
0
0
17
0
0
0
9
9
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
25
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
50
% _