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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR55
All Species:
5.15
Human Site:
S369
Identified Species:
10.3
UniProt:
Q9H6Y2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6Y2
NP_060176.2
383
42123
S369
L
R
E
E
G
E
D
S
M
A
Q
E
E
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535212
385
42379
S371
L
R
E
E
G
E
E
S
T
A
K
K
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX97
388
42592
A370
L
R
E
D
E
E
D
A
K
A
P
E
E
V
V
Rat
Rattus norvegicus
A1L112
384
42124
A369
L
R
E
D
E
E
E
A
K
A
P
E
E
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518168
201
21640
E188
A
G
L
R
E
E
P
E
A
P
E
D
G
A
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRF9
387
43154
E366
G
L
L
D
T
T
E
E
N
G
K
E
G
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T088
498
55303
N483
F
S
D
L
T
K
E
N
A
D
G
D
D
D
P
Honey Bee
Apis mellifera
XP_623745
423
47774
N407
R
Q
R
Q
L
K
C
N
L
P
S
S
K
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788545
584
64374
H550
I
R
F
W
G
V
E
H
L
Q
K
T
N
V
D
Poplar Tree
Populus trichocarpa
XP_002305841
348
38264
N334
R
K
G
A
K
R
K
N
E
N
A
N
G
A
A
Maize
Zea mays
NP_001132448
357
38978
Q344
S
K
K
A
G
K
G
Q
S
S
S
R
P
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565782
353
38407
S338
G
S
K
R
K
T
K
S
K
A
N
T
L
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.4
N.A.
87.3
89
N.A.
42
N.A.
N.A.
60.9
N.A.
27.5
29.5
N.A.
25
Protein Similarity:
100
N.A.
N.A.
96.3
N.A.
92.2
93.4
N.A.
47.7
N.A.
N.A.
77
N.A.
42.5
51
N.A.
41.9
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
53.3
46.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
66.6
66.6
N.A.
20
N.A.
N.A.
33.3
N.A.
40
46.6
N.A.
46.6
Percent
Protein Identity:
31.5
32.3
N.A.
31
N.A.
N.A.
Protein Similarity:
48.3
48.8
N.A.
48
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
0
0
17
17
42
9
0
0
25
25
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
25
0
0
17
0
0
9
0
17
9
9
17
% D
% Glu:
0
0
34
17
25
42
42
17
9
0
9
34
34
17
17
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
9
9
0
34
0
9
0
0
9
9
0
25
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
17
17
0
17
25
17
0
25
0
25
9
9
9
0
% K
% Leu:
34
9
17
9
9
0
0
0
17
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
9
9
9
9
9
9
9
% N
% Pro:
0
0
0
0
0
0
9
0
0
17
17
0
9
0
9
% P
% Gln:
0
9
0
9
0
0
0
9
0
9
9
0
0
0
0
% Q
% Arg:
17
42
9
17
0
9
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
17
0
0
0
0
0
25
9
9
17
9
0
0
17
% S
% Thr:
0
0
0
0
17
17
0
0
9
0
0
17
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
25
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _