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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR55
All Species:
19.09
Human Site:
S246
Identified Species:
38.18
UniProt:
Q9H6Y2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6Y2
NP_060176.2
383
42123
S246
W
N
G
F
G
A
T
S
D
R
F
A
L
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535212
385
42379
S248
W
N
G
F
G
A
T
S
D
R
F
A
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX97
388
42592
S247
W
N
G
F
G
A
T
S
D
R
F
A
L
R
A
Rat
Rattus norvegicus
A1L112
384
42124
S246
W
N
G
F
G
A
T
S
D
R
F
A
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518168
201
21640
A74
S
D
R
F
A
L
K
A
E
S
I
D
C
M
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRF9
387
43154
S243
W
N
G
F
G
A
T
S
D
R
F
A
V
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T088
498
55303
C362
W
G
Q
F
G
Y
H
C
D
M
Y
P
G
I
K
Honey Bee
Apis mellifera
XP_623745
423
47774
M293
V
G
T
N
K
G
K
M
Y
V
Y
N
W
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788545
584
64374
L185
I
A
S
A
T
V
E
L
S
L
E
K
A
H
E
Poplar Tree
Populus trichocarpa
XP_002305841
348
38264
S220
S
D
R
F
T
G
L
S
P
N
S
I
D
A
L
Maize
Zea mays
NP_001132448
357
38978
L229
S
V
D
T
M
L
K
L
D
E
D
T
L
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565782
353
38407
N222
R
F
V
D
L
A
P
N
S
V
D
A
L
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.4
N.A.
87.3
89
N.A.
42
N.A.
N.A.
60.9
N.A.
27.5
29.5
N.A.
25
Protein Similarity:
100
N.A.
N.A.
96.3
N.A.
92.2
93.4
N.A.
47.7
N.A.
N.A.
77
N.A.
42.5
51
N.A.
41.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
86.6
N.A.
26.6
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
26.6
N.A.
N.A.
100
N.A.
33.3
6.6
N.A.
0
Percent
Protein Identity:
31.5
32.3
N.A.
31
N.A.
N.A.
Protein Similarity:
48.3
48.8
N.A.
48
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
50
0
9
0
0
0
50
9
9
42
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
17
9
9
0
0
0
0
59
0
17
9
9
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
9
9
9
0
0
0
17
% E
% Phe:
0
9
0
67
0
0
0
0
0
0
42
0
0
0
0
% F
% Gly:
0
17
42
0
50
17
0
0
0
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% I
% Lys:
0
0
0
0
9
0
25
0
0
0
0
9
0
0
17
% K
% Leu:
0
0
0
0
9
17
9
17
0
9
0
0
50
9
9
% L
% Met:
0
0
0
0
9
0
0
9
0
9
0
0
0
9
0
% M
% Asn:
0
42
0
9
0
0
0
9
0
9
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
9
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
17
0
0
0
0
0
0
42
0
0
0
34
0
% R
% Ser:
25
0
9
0
0
0
0
50
17
9
9
0
0
0
9
% S
% Thr:
0
0
9
9
17
0
42
0
0
0
0
9
0
0
0
% T
% Val:
9
9
9
0
0
9
0
0
0
17
0
0
9
9
9
% V
% Trp:
50
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
9
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _