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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2orf43
All Species:
23.03
Human Site:
T180
Identified Species:
46.06
UniProt:
Q9H6V9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6V9
NP_068744.1
325
37319
T180
S
P
N
G
R
I
A
T
P
L
L
C
W
F
R
Chimpanzee
Pan troglodytes
XP_001141731
325
37314
T180
S
P
N
G
R
I
A
T
P
L
L
C
W
F
R
Rhesus Macaque
Macaca mulatta
XP_001109070
370
42722
T180
S
P
N
G
R
I
A
T
P
L
L
C
W
F
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVA5
326
37355
T181
S
P
N
G
K
F
A
T
P
F
L
C
Q
F
R
Rat
Rattus norvegicus
Q5HZX7
325
36863
T180
S
P
N
G
K
F
A
T
P
F
L
C
R
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511261
376
42498
V226
S
P
N
G
K
I
A
V
P
L
L
C
W
L
R
Chicken
Gallus gallus
Q5F477
324
36864
T177
S
P
Q
G
K
L
M
T
P
L
L
C
K
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124257
370
41457
T223
S
P
Q
G
K
V
M
T
P
V
L
C
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612097
307
35717
G172
M
P
L
Y
S
V
F
G
Y
I
F
F
S
F
F
Honey Bee
Apis mellifera
XP_396756
309
35863
K166
D
N
G
W
W
F
T
K
V
V
S
R
V
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182556
440
51097
G183
T
P
N
G
R
T
I
G
N
M
V
V
Y
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06522
304
34824
F172
S
L
F
S
Y
I
F
F
Y
W
I
L
S
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
84.8
N.A.
N.A.
66.2
65.8
N.A.
54.2
54.1
N.A.
42.4
N.A.
31.6
33.2
N.A.
30
Protein Similarity:
100
100
86.4
N.A.
N.A.
81.2
79
N.A.
67.2
72
N.A.
57.2
N.A.
51
54.1
N.A.
45.9
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
73.3
N.A.
80
60
N.A.
53.3
N.A.
13.3
0
N.A.
33.3
P-Site Similarity:
100
100
100
N.A.
N.A.
80
80
N.A.
86.6
73.3
N.A.
73.3
N.A.
26.6
6.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
50
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
9
0
0
25
17
9
0
17
9
9
0
50
17
% F
% Gly:
0
0
9
75
0
0
0
17
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
42
9
0
0
9
9
0
0
0
0
% I
% Lys:
0
0
0
0
42
0
0
9
0
0
0
0
9
0
0
% K
% Leu:
0
9
9
0
0
9
0
0
0
42
67
9
0
34
0
% L
% Met:
9
0
0
0
0
0
17
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
59
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
84
0
0
0
0
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
0
0
0
9
17
0
75
% R
% Ser:
75
0
0
9
9
0
0
0
0
0
9
0
17
0
0
% S
% Thr:
9
0
0
0
0
9
9
59
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
17
0
9
9
17
9
9
9
0
0
% V
% Trp:
0
0
0
9
9
0
0
0
0
9
0
0
34
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
17
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _