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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP2
All Species:
27.88
Human Site:
Y159
Identified Species:
51.11
UniProt:
Q9H6T0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T0
NP_079215.2
727
78401
Y159
P
D
M
F
F
S
F
Y
D
L
R
R
E
F
H
Chimpanzee
Pan troglodytes
XP_001167050
727
78395
Y159
P
D
M
F
F
S
F
Y
D
L
R
R
E
F
H
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
Y157
P
D
T
F
F
S
F
Y
D
L
R
R
E
F
H
Dog
Lupus familis
XP_851504
717
77019
Y159
P
D
T
F
F
S
F
Y
D
L
R
R
E
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G8
717
77342
Y159
P
D
T
F
F
S
F
Y
D
L
R
R
E
F
H
Rat
Rattus norvegicus
B2RYJ8
716
77222
Y159
P
D
T
F
F
S
F
Y
D
L
R
R
E
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505380
843
91210
Y268
S
D
D
F
F
S
F
Y
D
R
R
K
E
F
H
Chicken
Gallus gallus
Q5ZLR4
701
76929
P149
K
E
F
H
T
C
Y
P
S
S
A
A
V
K
D
Frog
Xenopus laevis
Q7ZY29
688
76408
C148
R
K
E
F
M
K
C
C
P
G
S
S
D
I
N
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
C147
K
K
E
F
H
K
C
C
P
N
A
G
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
S176
P
A
Y
Y
N
R
F
S
D
L
R
K
E
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
P109
N
E
L
C
V
P
H
P
L
H
H
Y
Y
D
I
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
H150
R
K
Y
P
N
A
P
H
I
T
D
V
K
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.8
93.1
N.A.
92
91
N.A.
61.6
67.4
57.3
60.8
N.A.
32.3
N.A.
32.1
41.7
Protein Similarity:
100
99.3
96.9
94.7
N.A.
94.3
93.6
N.A.
69.7
78.9
71.8
74.1
N.A.
44.1
N.A.
48.1
59.5
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
73.3
0
6.6
6.6
N.A.
46.6
N.A.
0
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
80
13.3
20
6.6
N.A.
60
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
0
16
8
0
0
0
% A
% Cys:
0
0
0
8
0
8
16
16
0
0
0
0
0
0
0
% C
% Asp:
0
54
8
0
0
0
0
0
62
0
8
0
8
16
8
% D
% Glu:
0
16
16
0
0
0
0
0
0
0
0
0
62
0
0
% E
% Phe:
0
0
8
70
54
0
62
0
0
0
0
0
0
62
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
8
8
0
8
8
0
8
8
0
0
0
54
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% I
% Lys:
16
24
0
0
0
16
0
0
0
0
0
16
8
8
8
% K
% Leu:
0
0
8
0
0
0
0
0
8
54
0
0
0
0
8
% L
% Met:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
16
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
54
0
0
8
0
8
8
16
16
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
8
0
0
0
8
62
47
0
0
0
% R
% Ser:
8
0
0
0
0
54
0
8
8
8
8
8
0
0
0
% S
% Thr:
0
0
31
0
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
8
0
0
8
54
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _