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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP2
All Species:
30
Human Site:
T566
Identified Species:
55
UniProt:
Q9H6T0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T0
NP_079215.2
727
78401
T566
S
R
V
L
M
G
G
T
L
G
R
S
G
M
S
Chimpanzee
Pan troglodytes
XP_001167050
727
78395
T566
S
R
V
L
M
G
G
T
L
G
R
S
G
M
S
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
T554
S
R
V
L
M
G
G
T
L
G
R
S
G
M
S
Dog
Lupus familis
XP_851504
717
77019
T556
S
R
V
L
M
G
G
T
L
G
R
S
G
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G8
717
77342
S556
S
R
V
L
M
G
G
S
L
S
R
S
G
L
S
Rat
Rattus norvegicus
B2RYJ8
716
77222
S555
S
R
V
L
M
G
G
S
L
S
R
S
G
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505380
843
91210
S672
S
L
V
L
M
G
G
S
L
N
R
S
G
L
S
Chicken
Gallus gallus
Q5ZLR4
701
76929
N540
V
L
M
G
G
T
L
N
R
S
G
L
S
P
P
Frog
Xenopus laevis
Q7ZY29
688
76408
M529
F
Q
C
S
A
E
E
M
N
F
V
L
M
G
G
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
T541
S
F
V
L
M
G
G
T
L
N
R
S
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
G639
D
M
N
M
V
L
N
G
G
L
A
S
P
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
K461
N
N
F
M
S
V
G
K
K
K
R
Y
I
E
V
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
N578
P
L
H
Y
P
P
P
N
H
P
H
A
Q
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.8
93.1
N.A.
92
91
N.A.
61.6
67.4
57.3
60.8
N.A.
32.3
N.A.
32.1
41.7
Protein Similarity:
100
99.3
96.9
94.7
N.A.
94.3
93.6
N.A.
69.7
78.9
71.8
74.1
N.A.
44.1
N.A.
48.1
59.5
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
73.3
0
0
80
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
6.6
6.6
86.6
N.A.
33.3
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% E
% Phe:
8
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
62
70
8
8
31
8
0
62
8
8
% G
% His:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% K
% Leu:
0
24
0
62
0
8
8
0
62
8
0
16
0
39
0
% L
% Met:
0
8
8
16
62
0
0
8
0
0
0
0
8
31
0
% M
% Asn:
8
8
8
0
0
0
8
16
8
16
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
8
8
0
0
8
0
0
8
8
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
47
0
0
0
0
0
0
8
0
70
0
0
0
0
% R
% Ser:
62
0
0
8
8
0
0
24
0
24
0
70
8
0
62
% S
% Thr:
0
0
0
0
0
8
0
39
0
0
0
0
0
0
8
% T
% Val:
8
0
62
0
8
8
0
0
0
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _