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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP2
All Species:
4.55
Human Site:
S269
Identified Species:
8.33
UniProt:
Q9H6T0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T0
NP_079215.2
727
78401
S269
R
G
L
P
W
Q
S
S
D
Q
D
V
A
R
F
Chimpanzee
Pan troglodytes
XP_001167050
727
78395
S269
R
G
L
P
W
Q
S
S
D
Q
D
V
A
R
F
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
G267
D
V
A
R
F
F
K
G
L
N
V
A
R
G
G
Dog
Lupus familis
XP_851504
717
77019
G269
D
V
A
R
F
F
K
G
L
N
I
A
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G8
717
77342
G269
D
V
A
R
F
F
K
G
L
N
I
A
R
G
G
Rat
Rattus norvegicus
B2RYJ8
716
77222
L269
V
A
R
F
F
K
G
L
N
I
A
R
G
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505380
843
91210
R378
S
S
D
Q
H
I
A
R
F
F
I
G
L
N
I
Chicken
Gallus gallus
Q5ZLR4
701
76929
C259
A
K
G
G
V
A
L
C
L
N
A
Q
G
R
R
Frog
Xenopus laevis
Q7ZY29
688
76408
L258
I
A
K
G
G
A
A
L
C
L
N
A
Q
G
R
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
C257
A
K
G
G
V
A
L
C
L
N
A
Q
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
L286
C
I
V
R
A
R
G
L
P
W
Q
S
S
D
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
G219
A
L
C
L
S
S
E
G
R
R
N
G
E
V
L
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
R260
C
L
N
T
H
G
R
R
N
G
E
V
M
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.8
93.1
N.A.
92
91
N.A.
61.6
67.4
57.3
60.8
N.A.
32.3
N.A.
32.1
41.7
Protein Similarity:
100
99.3
96.9
94.7
N.A.
94.3
93.6
N.A.
69.7
78.9
71.8
74.1
N.A.
44.1
N.A.
48.1
59.5
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
0
6.6
0
6.6
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
6.6
6.6
N.A.
6.6
20
N.A.
6.6
6.6
13.3
6.6
N.A.
20
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
16
24
0
8
24
16
0
0
0
24
31
16
0
0
% A
% Cys:
16
0
8
0
0
0
0
16
8
0
0
0
0
0
0
% C
% Asp:
24
0
8
0
0
0
0
0
16
0
16
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
8
31
24
0
0
8
8
0
0
0
0
16
% F
% Gly:
0
16
16
24
8
8
16
31
0
8
0
16
24
39
24
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
8
0
0
0
8
24
0
0
0
8
% I
% Lys:
0
16
8
0
0
8
24
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
16
8
0
0
16
24
39
8
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
16
39
16
0
0
8
0
% N
% Pro:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
16
0
0
0
16
8
16
8
0
8
% Q
% Arg:
16
0
8
31
0
8
8
16
8
8
0
8
24
31
24
% R
% Ser:
8
8
0
0
8
8
16
16
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
24
8
0
16
0
0
0
0
0
8
24
0
16
8
% V
% Trp:
0
0
0
0
16
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _