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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX33
All Species:
4.55
Human Site:
S540
Identified Species:
6.25
UniProt:
Q9H6R0
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R0
NP_064547.2
707
78741
S540
S
V
L
H
N
P
P
S
R
R
E
E
V
Q
G
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
K861
N
S
I
F
Y
R
P
K
D
K
V
V
H
A
D
Rhesus Macaque
Macaca mulatta
XP_001101396
711
79026
S544
S
V
L
H
N
P
P
S
R
R
E
E
V
Q
G
Dog
Lupus familis
XP_848932
616
69314
V454
P
P
S
R
R
D
E
V
Q
A
M
R
K
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80VY9
698
78328
A531
S
V
L
Y
N
P
P
A
R
R
D
E
V
Q
S
Rat
Rattus norvegicus
Q5XI69
779
88496
D529
N
V
F
I
R
P
V
D
P
E
Y
Q
K
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521779
621
67474
G460
V
D
Q
L
D
L
L
G
A
L
D
R
K
D
E
Chicken
Gallus gallus
XP_001233396
657
73561
A490
S
V
L
Y
N
P
P
A
R
R
D
E
V
Q
S
Frog
Xenopus laevis
Q5XH12
748
85094
P526
N
C
F
I
D
L
P
P
E
A
K
E
L
D
L
Zebra Danio
Brachydanio rerio
XP_002663995
1224
139696
D1027
N
V
F
Y
R
P
K
D
K
Q
A
L
A
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122093
694
76860
A532
S
V
F
T
D
P
P
A
K
R
Q
Q
A
Y
V
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
E998
N
I
F
Y
R
P
K
E
K
Q
D
H
A
D
Q
Sea Urchin
Strong. purpuratus
O17438
455
51461
F293
G
I
D
D
L
V
H
F
D
F
M
D
P
P
A
Poplar Tree
Populus trichocarpa
XP_002311345
658
74028
G495
K
C
F
A
S
P
D
G
D
H
L
T
L
I
N
Maize
Zea mays
NP_001147775
692
77358
E515
S
I
F
F
S
V
R
E
K
L
E
E
A
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
E973
N
I
F
Y
R
P
R
E
K
Q
A
Q
A
D
Q
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
D941
N
V
F
Y
R
P
K
D
R
Q
L
E
A
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
93.9
79.3
N.A.
92.6
34.4
N.A.
45.9
80.1
27.8
26.2
N.A.
N.A.
48.5
25.9
29.7
Protein Similarity:
100
45
95.7
84.4
N.A.
96.4
51.3
N.A.
56
87.2
47.5
38.3
N.A.
N.A.
66.9
38.6
42.5
P-Site Identity:
100
6.6
100
0
N.A.
73.3
13.3
N.A.
0
73.3
13.3
13.3
N.A.
N.A.
33.3
6.6
0
P-Site Similarity:
100
26.6
100
13.3
N.A.
93.3
33.3
N.A.
13.3
93.3
40
40
N.A.
N.A.
66.6
46.6
13.3
Percent
Protein Identity:
45.1
46.6
N.A.
26.2
26.4
N.A.
Protein Similarity:
63.9
66.4
N.A.
38.9
40.2
N.A.
P-Site Identity:
6.6
20
N.A.
6.6
26.6
N.A.
P-Site Similarity:
20
46.6
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
0
0
18
6
12
12
0
36
6
18
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
6
18
6
6
18
18
0
24
6
0
36
6
% D
% Glu:
0
0
0
0
0
0
6
18
6
6
18
42
0
6
6
% E
% Phe:
0
0
53
12
0
0
0
6
0
6
0
0
0
0
6
% F
% Gly:
6
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% G
% His:
0
0
0
12
0
0
6
0
0
6
0
6
6
0
0
% H
% Ile:
0
24
6
12
0
0
0
0
0
0
0
0
0
6
0
% I
% Lys:
6
0
0
0
0
0
18
6
30
6
6
0
18
6
0
% K
% Leu:
0
0
24
6
6
12
6
0
0
12
12
6
12
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
42
0
0
0
24
0
0
0
0
0
0
0
0
0
6
% N
% Pro:
6
6
0
0
0
65
42
6
6
0
0
0
6
6
0
% P
% Gln:
0
0
6
0
0
0
0
0
6
24
6
18
0
24
18
% Q
% Arg:
0
0
0
6
36
6
12
0
30
30
0
12
0
6
0
% R
% Ser:
36
6
6
0
12
0
0
12
0
0
0
0
0
0
18
% S
% Thr:
0
0
0
6
0
0
0
0
0
0
0
6
0
0
0
% T
% Val:
6
48
0
0
0
12
6
6
0
0
6
6
24
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
36
6
0
0
0
0
0
6
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _