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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX33
All Species:
20.61
Human Site:
S181
Identified Species:
28.33
UniProt:
Q9H6R0
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R0
NP_064547.2
707
78741
S181
M
L
L
R
E
A
I
S
D
S
L
L
R
K
Y
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S510
M
L
L
R
E
F
L
S
E
P
D
L
A
S
Y
Rhesus Macaque
Macaca mulatta
XP_001101396
711
79026
S181
M
L
L
R
E
A
I
S
D
S
L
L
R
K
Y
Dog
Lupus familis
XP_848932
616
69314
K127
K
A
A
Q
R
R
R
K
E
L
R
K
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80VY9
698
78328
S172
M
L
L
R
E
A
I
S
D
S
L
L
R
K
Y
Rat
Rattus norvegicus
Q5XI69
779
88496
G160
C
L
L
K
H
I
L
G
D
P
N
L
N
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521779
621
67474
A133
S
C
V
I
L
D
E
A
H
E
R
T
V
H
T
Chicken
Gallus gallus
XP_001233396
657
73561
V159
H
T
D
V
L
F
G
V
V
K
A
A
Q
K
K
Frog
Xenopus laevis
Q5XH12
748
85094
S174
M
L
R
R
E
M
M
S
N
P
L
L
S
S
Y
Zebra Danio
Brachydanio rerio
XP_002663995
1224
139696
I676
M
L
L
R
E
C
L
I
D
P
D
L
G
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122093
694
76860
T176
M
M
V
R
E
A
M
T
D
E
I
L
S
D
Y
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
I647
M
L
L
R
E
C
L
I
D
P
D
L
S
G
Y
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002311345
658
74028
P165
S
C
Q
R
K
F
P
P
L
K
L
I
I
M
S
Maize
Zea mays
NP_001147775
692
77358
S172
L
L
K
K
V
Q
H
S
R
A
N
T
N
K
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
I622
M
L
L
R
E
I
L
I
D
E
N
L
S
Q
Y
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L590
M
L
Q
R
E
A
L
L
D
P
E
M
S
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
93.9
79.3
N.A.
92.6
34.4
N.A.
45.9
80.1
27.8
26.2
N.A.
N.A.
48.5
25.9
29.7
Protein Similarity:
100
45
95.7
84.4
N.A.
96.4
51.3
N.A.
56
87.2
47.5
38.3
N.A.
N.A.
66.9
38.6
42.5
P-Site Identity:
100
53.3
100
0
N.A.
100
33.3
N.A.
0
6.6
53.3
53.3
N.A.
N.A.
46.6
53.3
0
P-Site Similarity:
100
66.6
100
13.3
N.A.
100
53.3
N.A.
13.3
13.3
66.6
66.6
N.A.
N.A.
80
60
0
Percent
Protein Identity:
45.1
46.6
N.A.
26.2
26.4
N.A.
Protein Similarity:
63.9
66.4
N.A.
38.9
40.2
N.A.
P-Site Identity:
13.3
20
N.A.
53.3
53.3
N.A.
P-Site Similarity:
26.6
40
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
30
0
6
0
6
6
6
6
0
0
% A
% Cys:
6
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
6
0
0
53
0
18
0
0
6
0
% D
% Glu:
0
0
0
0
59
0
6
0
12
18
6
0
0
0
0
% E
% Phe:
0
0
0
0
0
18
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
6
6
0
0
0
0
6
6
0
% G
% His:
6
0
0
0
6
0
6
0
6
0
0
0
0
6
0
% H
% Ile:
0
0
0
6
0
12
18
18
0
0
6
6
6
0
0
% I
% Lys:
6
0
6
12
6
0
0
6
0
12
0
6
0
42
6
% K
% Leu:
6
65
48
0
12
0
36
6
6
6
30
59
6
0
6
% L
% Met:
59
6
0
0
0
6
12
0
0
0
0
6
0
6
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
18
0
12
0
6
% N
% Pro:
0
0
0
0
0
0
6
6
0
36
0
0
0
6
0
% P
% Gln:
0
0
12
6
0
6
0
0
0
0
0
0
6
12
0
% Q
% Arg:
0
0
6
65
6
6
6
0
6
0
12
0
18
0
0
% R
% Ser:
12
0
0
0
0
0
0
36
0
18
0
0
30
12
6
% S
% Thr:
0
6
0
0
0
0
0
6
0
0
0
12
0
0
6
% T
% Val:
0
0
12
6
6
0
0
6
6
0
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _