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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX33
All Species:
13.33
Human Site:
S140
Identified Species:
18.33
UniProt:
Q9H6R0
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R0
NP_064547.2
707
78741
S140
I
S
L
A
T
R
V
S
D
E
K
R
T
E
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
A469
M
S
V
A
A
R
V
A
R
E
M
G
V
K
L
Rhesus Macaque
Macaca mulatta
XP_001101396
711
79026
S140
I
S
L
A
T
R
V
S
D
E
K
R
T
E
L
Dog
Lupus familis
XP_848932
616
69314
R86
L
T
D
G
M
L
L
R
E
A
I
S
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80VY9
698
78328
S131
I
S
L
A
T
R
V
S
D
E
K
R
T
E
L
Rat
Rattus norvegicus
Q5XI69
779
88496
A119
I
S
V
A
Q
R
V
A
E
E
M
K
C
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521779
621
67474
V92
G
N
L
V
G
Y
T
V
R
F
D
D
V
T
S
Chicken
Gallus gallus
XP_001233396
657
73561
K118
T
S
D
E
T
R
I
K
F
L
T
D
G
M
L
Frog
Xenopus laevis
Q5XH12
748
85094
A133
V
W
L
A
M
R
V
A
D
E
M
D
V
N
I
Zebra Danio
Brachydanio rerio
XP_002663995
1224
139696
S635
M
S
V
A
K
R
V
S
E
E
Y
G
C
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122093
694
76860
A135
V
S
V
A
R
R
V
A
Q
E
Q
G
V
E
A
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
A606
M
S
V
A
K
R
V
A
E
E
Y
G
C
K
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002311345
658
74028
S124
A
L
L
D
P
Y
L
S
R
Y
S
V
I
I
V
Maize
Zea mays
NP_001147775
692
77358
L131
K
Y
M
T
D
G
L
L
L
R
E
A
L
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
A581
M
S
V
A
K
R
V
A
E
E
F
G
C
R
L
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
A549
V
S
V
A
K
R
V
A
E
E
V
G
C
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
93.9
79.3
N.A.
92.6
34.4
N.A.
45.9
80.1
27.8
26.2
N.A.
N.A.
48.5
25.9
29.7
Protein Similarity:
100
45
95.7
84.4
N.A.
96.4
51.3
N.A.
56
87.2
47.5
38.3
N.A.
N.A.
66.9
38.6
42.5
P-Site Identity:
100
40
100
6.6
N.A.
100
46.6
N.A.
6.6
26.6
40
46.6
N.A.
N.A.
40
40
0
P-Site Similarity:
100
66.6
100
33.3
N.A.
100
73.3
N.A.
13.3
33.3
60
66.6
N.A.
N.A.
66.6
73.3
0
Percent
Protein Identity:
45.1
46.6
N.A.
26.2
26.4
N.A.
Protein Similarity:
63.9
66.4
N.A.
38.9
40.2
N.A.
P-Site Identity:
13.3
0
N.A.
40
33.3
N.A.
P-Site Similarity:
26.6
20
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
65
6
0
0
42
0
6
0
6
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
30
6
0
% C
% Asp:
0
0
12
6
6
0
0
0
24
0
6
18
6
0
6
% D
% Glu:
0
0
0
6
0
0
0
0
36
65
6
0
0
24
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
6
6
0
0
0
0
% F
% Gly:
6
0
0
6
6
6
0
0
0
0
0
36
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
24
0
0
0
0
0
6
0
0
0
6
0
6
6
6
% I
% Lys:
6
0
0
0
24
0
0
6
0
0
18
6
0
18
0
% K
% Leu:
6
6
36
0
0
6
18
6
6
6
0
0
6
6
59
% L
% Met:
24
0
6
0
12
0
0
0
0
0
18
0
0
6
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
6
0
0
0
6
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
6
71
0
6
18
6
0
18
0
6
0
% R
% Ser:
0
65
0
0
0
0
0
30
0
0
6
6
0
6
6
% S
% Thr:
6
6
0
6
24
0
6
0
0
0
6
0
18
12
0
% T
% Val:
18
0
42
6
0
0
65
6
0
0
6
6
24
0
12
% V
% Trp:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
12
0
0
0
6
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _