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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RERGL All Species: 25.76
Human Site: S185 Identified Species: 47.22
UniProt: Q9H628 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H628 NP_079006.1 205 23855 S185 L K E K R R P S G S K S M A K
Chimpanzee Pan troglodytes XP_520774 204 23387 S184 L K E K R R P S G S K S M A K
Rhesus Macaque Macaca mulatta XP_001095306 204 23785 S184 L K E K R R P S G S K S M A K
Dog Lupus familis XP_543785 221 25239 S201 L K E K R R P S G S K S M A K
Cat Felis silvestris
Mouse Mus musculus Q6IMB1 242 27049 V211 G E R R R A S V I P R P R S P
Rat Rattus norvegicus Q6IMA3 242 26956 I211 G E R R R A S I I P R P R S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519319 143 16116 G124 R D K R R P S G S K S V A K L
Chicken Gallus gallus XP_416411 202 22676 S182 A K E K R R P S G S K S M A K
Frog Xenopus laevis Q8AVS6 248 27595 I218 S E R R K N S I I P R P K S P
Zebra Danio Brachydanio rerio Q6DGN0 205 23206 S185 K E R R R R P S G S K S M A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648054 207 23355 S176 L C K E V L A S K R K S K Q S
Honey Bee Apis mellifera XP_001119889 216 24087 A183 L C R E V L A A R R R N K Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01387 229 25331 S197 K Q R Q Q G Q S T P R A L P P
Conservation
Percent
Protein Identity: 100 92.1 97 84.1 N.A. 32.6 32.6 N.A. 47.3 69.2 29.8 59.5 N.A. 33.8 33.3 N.A. N.A.
Protein Similarity: 100 94.1 98.5 86.8 N.A. 50.4 48.7 N.A. 59 80.4 43.5 74.6 N.A. 52.6 50.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 6.6 93.3 0 73.3 N.A. 26.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 33.3 33.3 N.A. 20 93.3 33.3 86.6 N.A. 40 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29.6
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41.9
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 16 16 8 0 0 0 8 8 47 0 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 31 39 16 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 0 0 8 0 8 47 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 24 0 0 0 0 0 0 % I
% Lys: 16 39 16 39 8 0 0 0 8 8 54 0 24 8 47 % K
% Leu: 47 0 0 0 0 16 0 0 0 0 0 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 47 0 0 31 0 24 0 8 31 % P
% Gln: 0 8 0 8 8 0 8 0 0 0 0 0 0 16 0 % Q
% Arg: 8 0 47 39 70 47 0 0 8 16 39 0 16 0 0 % R
% Ser: 8 0 0 0 0 0 31 62 8 47 8 54 0 24 16 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 16 0 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _