KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL8
All Species:
14.24
Human Site:
Y35
Identified Species:
26.11
UniProt:
Q9H568
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H568
NP_110439.2
366
41360
Y35
V
F
P
N
I
V
N
Y
L
P
C
K
E
N
P
Chimpanzee
Pan troglodytes
XP_001156798
366
41310
Y35
V
F
P
N
I
V
N
Y
L
P
C
K
E
N
P
Rhesus Macaque
Macaca mulatta
XP_001090405
366
41293
Y35
V
F
P
N
I
V
N
Y
L
P
C
K
E
N
P
Dog
Lupus familis
XP_544535
432
48309
Y101
V
F
P
S
I
V
N
Y
I
P
C
R
E
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P68035
377
42000
R41
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515705
376
41051
T41
Q
I
S
P
D
N
M
T
A
S
G
L
Q
N
R
Chicken
Gallus gallus
P68139
377
42033
R41
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Frog
Xenopus laevis
P04751
377
41997
R41
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Zebra Danio
Brachydanio rerio
NP_001002066
377
41986
R41
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
R41
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Fruit Fly
Dros. melanogaster
P02574
376
41768
R40
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508841
376
41759
R40
P
S
I
V
G
R
P
R
H
Q
G
V
M
V
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
NP_116614
375
41671
R39
P
S
I
V
G
R
P
R
H
Q
G
I
M
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.5
66.4
N.A.
N.A.
32.8
N.A.
32.7
33.1
32.8
32.8
32.8
32.1
N.A.
32.7
N.A.
Protein Similarity:
100
100
98.3
75.4
N.A.
N.A.
51.1
N.A.
52.3
51.7
51.4
51.1
51.1
52.1
N.A.
51.3
N.A.
P-Site Identity:
100
100
100
80
N.A.
N.A.
0
N.A.
6.6
0
0
0
0
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
N.A.
0
N.A.
13.3
0
0
0
0
0
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% E
% Phe:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
62
0
0
0
0
0
70
0
0
0
62
% G
% His:
0
0
0
0
0
0
0
0
62
0
0
0
0
0
0
% H
% Ile:
0
8
62
0
31
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
24
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
62
0
0
% M
% Asn:
0
0
0
24
0
8
31
0
0
0
0
0
0
39
0
% N
% Pro:
62
0
31
8
0
0
62
0
0
31
0
0
0
0
31
% P
% Gln:
8
0
0
0
0
0
0
0
0
62
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
62
0
62
0
0
0
8
0
0
8
% R
% Ser:
0
62
8
8
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
31
0
0
62
0
31
0
0
0
0
0
54
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _