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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL8
All Species:
13.33
Human Site:
S244
Identified Species:
24.44
UniProt:
Q9H568
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H568
NP_110439.2
366
41360
S244
T
Y
Q
L
P
D
G
S
R
V
E
L
T
P
M
Chimpanzee
Pan troglodytes
XP_001156798
366
41310
S244
T
Y
Q
L
P
D
G
S
R
V
E
L
T
P
M
Rhesus Macaque
Macaca mulatta
XP_001090405
366
41293
S244
T
Y
Q
L
P
D
G
S
R
V
E
L
T
P
M
Dog
Lupus familis
XP_544535
432
48309
T310
T
Y
Q
L
P
D
G
T
P
V
E
L
T
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P68035
377
42000
Q248
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515705
376
41051
A247
Y
K
L
P
D
G
N
A
I
S
V
P
E
E
D
Chicken
Gallus gallus
P68139
377
42033
Q248
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Frog
Xenopus laevis
P04751
377
41997
Q248
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Zebra Danio
Brachydanio rerio
NP_001002066
377
41986
Q248
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
Q248
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Fruit Fly
Dros. melanogaster
P02574
376
41768
Q247
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508841
376
41759
Q247
S
Y
E
L
P
D
G
Q
V
I
T
V
G
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
NP_116614
375
41671
Q246
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.5
66.4
N.A.
N.A.
32.8
N.A.
32.7
33.1
32.8
32.8
32.8
32.1
N.A.
32.7
N.A.
Protein Similarity:
100
100
98.3
75.4
N.A.
N.A.
51.1
N.A.
52.3
51.7
51.4
51.1
51.1
52.1
N.A.
51.3
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
N.A.
33.3
N.A.
0
33.3
33.3
33.3
33.3
33.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
N.A.
60
N.A.
6.6
60
60
60
60
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
93
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
62
0
0
0
0
0
0
0
31
0
8
8
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
93
0
0
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
62
0
54
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
93
0
0
0
0
0
0
0
31
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
62
0
% N
% Pro:
0
0
0
8
93
0
0
0
8
0
0
8
0
31
0
% P
% Gln:
0
0
31
0
0
0
0
62
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% R
% Ser:
62
0
0
0
0
0
0
24
0
8
0
0
0
0
0
% S
% Thr:
31
0
0
0
0
0
0
8
0
0
62
0
31
0
0
% T
% Val:
0
0
0
0
0
0
0
0
62
31
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _