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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESF1
All Species:
21.82
Human Site:
S663
Identified Species:
43.64
UniProt:
Q9H501
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H501
NP_057733.2
851
98796
S663
A
S
E
E
E
L
P
S
D
V
D
L
N
D
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083468
849
98477
S661
A
S
E
E
E
L
P
S
D
V
D
L
N
D
P
Dog
Lupus familis
XP_534341
849
98634
S659
A
S
E
D
E
L
P
S
D
V
D
L
N
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1V3
845
98030
S657
D
S
E
D
E
L
P
S
D
V
D
F
N
D
P
Rat
Rattus norvegicus
Q76MT4
842
97516
S654
A
S
E
D
E
I
P
S
D
V
D
L
N
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514209
839
97846
P651
T
S
E
D
E
L
P
P
D
V
D
L
N
D
P
Chicken
Gallus gallus
NP_001026690
838
97135
S653
M
S
E
D
E
I
P
S
D
V
N
L
N
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956039
757
88784
K589
E
S
K
K
N
R
K
K
E
E
E
R
T
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569906
771
88512
K598
K
T
K
Q
D
K
K
K
K
K
K
K
G
K
D
Honey Bee
Apis mellifera
XP_624350
533
62517
N383
L
D
N
H
E
K
N
N
R
L
S
H
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781121
795
92011
F605
I
D
L
N
D
S
F
F
K
D
S
L
K
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06344
628
72391
E478
K
K
H
T
N
D
E
E
E
I
E
K
N
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
84.6
N.A.
81.1
80
N.A.
69.2
60.9
N.A.
52.6
N.A.
34
26.5
N.A.
41.3
Protein Similarity:
100
N.A.
96.9
91.4
N.A.
90.1
89.6
N.A.
81.7
76.6
N.A.
68
N.A.
54.4
44.7
N.A.
62.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
80
86.6
N.A.
80
73.3
N.A.
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
100
N.A.
86.6
93.3
N.A.
33.3
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
42
17
9
0
0
59
9
50
0
0
59
9
% D
% Glu:
9
0
59
17
67
0
9
9
17
9
17
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
17
0
0
0
9
0
0
0
0
0
% I
% Lys:
17
9
17
9
0
17
17
17
17
9
9
17
17
17
17
% K
% Leu:
9
0
9
0
0
42
0
0
0
9
0
59
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
17
0
9
9
0
0
9
0
67
0
0
% N
% Pro:
0
0
0
0
0
0
59
9
0
0
0
0
0
9
59
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
9
0
0
9
0
0
0
% R
% Ser:
0
67
0
0
0
9
0
50
0
0
17
0
0
0
9
% S
% Thr:
9
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _