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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHA4 All Species: 6.36
Human Site: S575 Identified Species: 23.33
UniProt: Q9H4M7 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4M7 NP_001154826.1 779 85401 S575 P E G R H L P S P Q L G T K A
Chimpanzee Pan troglodytes XP_512804 472 51801 L290 G T R A S M V L L P G P P L E
Rhesus Macaque Macaca mulatta XP_001112238 641 70289 G459 S G L E Q E L G T L R E T L E
Dog Lupus familis XP_541508 778 85135 S575 P E S H H P A S P Q P R T K V
Cat Felis silvestris
Mouse Mus musculus Q8VC98 588 64820 R406 E A A L E L T R Q Q L G Q A T
Rat Rattus norvegicus P60669 779 85624 S578 P E C R Q Q S S P L L R T K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421001 1256 142432 S819 A S L T T V E S K P S V P Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.8 66.7 87 N.A. 63.5 80.2 N.A. N.A. 25.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 60.2 70 90.2 N.A. 67.9 86.2 N.A. N.A. 38 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 53.3 N.A. 26.6 60 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 6.6 53.3 N.A. 26.6 60 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 15 15 0 0 15 0 0 0 0 0 0 15 29 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 43 0 15 15 15 15 0 0 0 0 15 0 0 29 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 15 15 0 0 0 0 15 0 0 15 29 0 0 0 % G
% His: 0 0 0 15 29 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 15 0 0 0 0 43 0 % K
% Leu: 0 0 29 15 0 29 15 15 15 29 43 0 0 29 0 % L
% Met: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 43 0 0 0 0 15 15 0 43 29 15 15 29 0 0 % P
% Gln: 0 0 0 0 29 15 0 0 15 43 0 0 15 15 0 % Q
% Arg: 0 0 15 29 0 0 0 15 0 0 15 29 0 0 0 % R
% Ser: 15 15 15 0 15 0 15 58 0 0 15 0 0 0 15 % S
% Thr: 0 15 0 15 15 0 15 0 15 0 0 0 58 0 15 % T
% Val: 0 0 0 0 0 15 15 0 0 0 0 15 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _