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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
29.39
Human Site:
Y635
Identified Species:
40.42
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y635
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Y431
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y636
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Dog
Lupus familis
XP_532604
646
71462
Y635
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y620
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Rat
Rattus norvegicus
Q9R011
615
68782
Y605
D
L
R
Q
R
L
R
Y
A
L
R
L
L
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
E783
L
E
L
K
N
R
M
E
Y
A
L
N
M
L
L
Chicken
Gallus gallus
XP_422425
639
71988
Y628
E
L
Q
H
C
L
R
Y
I
L
K
L
L
Q
E
Frog
Xenopus laevis
P70032
598
68193
S586
T
M
V
E
K
L
Q
S
S
K
S
A
V
A
H
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
L631
S
P
E
L
R
Q
R
L
H
Y
V
V
Q
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
K566
K
I
R
Y
A
Q
E
K
L
R
K
M
L
E
K
Honey Bee
Apis mellifera
XP_396707
575
66141
L565
L
A
Y
A
H
E
K
L
V
L
M
L
S
N
P
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
L616
S
T
S
S
N
V
R
L
E
S
A
A
D
I
Q
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
T577
N
M
L
D
K
K
T
T
T
T
T
A
A
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
V616
E
N
K
Q
V
T
Y
V
A
R
K
E
T
E
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
N429
K
W
Q
G
N
N
N
N
S
N
N
E
K
I
E
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
E686
Y
P
E
S
N
F
R
E
K
L
T
L
I
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
46.6
6.6
13.3
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
80
46.6
20
N.A.
33.3
20
13.3
20
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
6
0
0
0
42
6
6
18
6
12
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
36
0
0
6
0
0
0
0
0
0
0
0
6
0
36
% D
% Glu:
12
6
12
6
0
6
6
12
6
0
0
12
0
12
18
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
6
6
0
0
0
6
0
0
0
0
0
6
% H
% Ile:
0
6
0
0
0
0
0
0
6
0
0
0
6
12
0
% I
% Lys:
12
0
6
6
12
6
6
6
6
6
18
0
6
6
6
% K
% Leu:
12
42
12
6
0
48
0
18
6
53
6
53
48
12
12
% L
% Met:
0
12
0
0
0
0
6
0
0
0
6
6
6
0
0
% M
% Asn:
6
6
0
0
24
6
6
6
0
6
6
6
0
6
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
12
42
0
12
6
0
0
0
0
0
6
6
6
% Q
% Arg:
0
0
42
0
42
6
59
0
0
12
36
0
0
36
0
% R
% Ser:
12
0
6
12
0
0
0
6
12
6
6
0
6
0
0
% S
% Thr:
6
6
0
0
0
6
6
6
6
6
12
0
6
0
0
% T
% Val:
0
0
6
0
6
6
0
6
6
0
6
6
6
0
6
% V
% Trp:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
6
6
0
0
6
42
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _