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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
25.76
Human Site:
Y534
Identified Species:
35.42
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y534
P
Q
L
G
I
L
R
Y
F
A
S
Y
M
E
Q
Chimpanzee
Pan troglodytes
XP_513131
442
49225
V333
L
A
Q
P
E
P
L
V
W
V
S
K
W
V
D
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y535
P
Q
L
S
I
L
R
Y
F
T
S
Y
M
E
Q
Dog
Lupus familis
XP_532604
646
71462
Y534
P
Q
L
G
V
L
R
Y
F
A
S
Y
M
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y519
P
Q
L
G
I
L
R
Y
F
A
S
Y
M
E
Q
Rat
Rattus norvegicus
Q9R011
615
68782
Y504
P
Q
L
G
I
L
R
Y
F
A
S
Y
M
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
Y683
S
Q
V
T
V
L
K
Y
F
S
H
Y
M
E
E
Chicken
Gallus gallus
XP_422425
639
71988
Y527
G
Q
M
S
V
L
R
Y
F
A
S
Y
M
E
Q
Frog
Xenopus laevis
P70032
598
68193
A487
M
S
E
H
L
L
K
A
G
A
N
T
T
P
R
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
L531
S
Q
K
H
I
V
D
L
M
A
N
Y
M
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
I468
S
Y
F
K
R
Y
M
I
E
H
L
V
K
A
G
Honey Bee
Apis mellifera
XP_396707
575
66141
E467
F
F
L
K
Y
M
K
E
H
L
M
K
A
G
C
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
R512
P
T
L
R
V
W
F
R
T
K
S
A
I
V
L
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
T479
L
K
A
G
A
A
M
T
P
R
E
S
D
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
R517
D
Q
V
T
Y
I
Q
R
G
K
N
D
R
Q
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
F331
E
E
R
S
E
S
K
F
T
T
K
K
D
A
K
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
F588
R
H
L
E
V
V
D
F
F
A
K
Y
M
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
6.6
86.6
93.3
N.A.
100
100
N.A.
46.6
73.3
13.3
46.6
N.A.
0
6.6
20
6.6
P-Site Similarity:
100
13.3
86.6
100
N.A.
100
100
N.A.
80
86.6
40
60
N.A.
0
20
33.3
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
6
6
0
6
0
48
0
6
6
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
6
0
0
0
0
0
12
0
0
0
0
6
12
0
12
% D
% Glu:
6
6
6
6
12
0
0
6
6
0
6
0
0
48
6
% E
% Phe:
6
6
6
0
0
0
6
12
48
0
0
0
0
0
0
% F
% Gly:
6
0
0
30
0
0
0
0
12
0
0
0
0
6
6
% G
% His:
0
6
0
12
0
0
0
0
6
6
6
0
0
0
0
% H
% Ile:
0
0
0
0
30
6
0
6
0
0
0
0
6
0
0
% I
% Lys:
0
6
6
12
0
0
24
0
0
12
12
18
6
6
6
% K
% Leu:
12
0
48
0
6
48
6
6
0
6
6
0
0
0
6
% L
% Met:
6
0
6
0
0
6
12
0
6
0
6
0
53
0
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
18
0
0
0
0
% N
% Pro:
36
0
0
6
0
6
0
0
6
0
0
0
0
6
0
% P
% Gln:
0
53
6
0
0
0
6
0
0
0
0
0
0
6
42
% Q
% Arg:
6
0
6
6
6
0
36
12
0
6
0
0
6
0
6
% R
% Ser:
18
6
0
18
0
6
0
0
0
6
48
6
0
6
0
% S
% Thr:
0
6
0
12
0
0
0
6
12
12
0
6
6
0
0
% T
% Val:
0
0
12
0
30
12
0
6
0
6
0
6
0
12
0
% V
% Trp:
0
0
0
0
0
6
0
0
6
0
0
0
6
0
0
% W
% Tyr:
0
6
0
0
12
6
0
42
0
0
0
53
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _