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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
31.21
Human Site:
Y506
Identified Species:
42.92
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y506
A
N
R
K
T
V
H
Y
N
P
T
S
T
K
H
Chimpanzee
Pan troglodytes
XP_513131
442
49225
C307
T
V
V
E
S
A
L
C
A
L
R
N
C
V
A
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y507
A
N
R
K
T
V
H
Y
N
P
T
S
T
K
H
Dog
Lupus familis
XP_532604
646
71462
Y506
A
N
R
K
T
V
H
Y
N
P
T
S
T
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y491
A
N
R
K
T
V
H
Y
N
P
T
S
T
K
H
Rat
Rattus norvegicus
Q9R011
615
68782
Y476
A
N
R
K
T
V
H
Y
N
P
T
S
T
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
Y655
P
D
K
K
T
V
H
Y
Y
A
E
L
G
Q
C
Chicken
Gallus gallus
XP_422425
639
71988
Y499
P
N
H
K
T
V
H
Y
N
P
T
N
S
K
H
Frog
Xenopus laevis
P70032
598
68193
R460
T
E
S
Y
L
N
V
R
S
Y
P
T
T
L
T
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
Y503
D
Q
R
R
T
V
H
Y
C
L
T
N
N
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
T442
I
D
K
D
G
K
E
T
Y
M
T
T
T
D
Y
Honey Bee
Apis mellifera
XP_396707
575
66141
Y441
N
R
E
G
N
E
L
Y
Y
T
V
K
E
Y
P
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
L474
G
L
Q
K
K
M
T
L
L
K
Y
F
R
S
Y
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
L453
L
G
S
Y
D
S
T
L
H
K
K
V
T
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
V476
E
V
W
V
K
K
W
V
D
Y
S
S
K
Y
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
F305
K
P
M
S
Y
N
A
F
D
L
I
S
S
L
S
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
Y556
A
D
A
E
E
F
W
Y
I
S
Y
D
D
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
33.3
73.3
6.6
53.3
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
53.3
86.6
20
66.6
N.A.
40
6.6
26.6
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
6
0
0
6
6
0
6
6
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
6
6
0
0
0
6
0
6
% C
% Asp:
6
18
0
6
6
0
0
0
12
0
0
6
6
6
0
% D
% Glu:
6
6
6
12
6
6
6
0
0
0
6
0
6
0
6
% E
% Phe:
0
0
0
0
0
6
0
6
0
0
0
6
0
0
0
% F
% Gly:
6
6
0
6
6
0
0
0
0
0
0
0
6
0
6
% G
% His:
0
0
6
0
0
0
48
0
6
0
0
0
0
0
42
% H
% Ile:
6
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% I
% Lys:
6
0
12
48
12
12
0
0
0
12
6
6
6
42
0
% K
% Leu:
6
6
0
0
6
0
12
12
6
18
0
6
0
18
6
% L
% Met:
0
0
6
0
0
6
0
0
0
6
0
0
0
0
0
% M
% Asn:
6
36
0
0
6
12
0
0
36
0
0
18
6
0
0
% N
% Pro:
12
6
0
0
0
0
0
0
0
36
6
0
0
0
6
% P
% Gln:
0
6
6
0
0
0
0
0
0
0
0
0
0
6
0
% Q
% Arg:
0
6
36
6
0
0
0
6
0
0
6
0
6
6
0
% R
% Ser:
0
0
12
6
6
6
0
0
6
6
6
42
12
6
6
% S
% Thr:
12
0
0
0
48
0
12
6
0
6
48
12
48
0
6
% T
% Val:
0
12
6
6
0
48
6
6
0
0
6
6
0
6
0
% V
% Trp:
0
0
6
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
6
0
0
59
18
12
12
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _