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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
27.27
Human Site:
S626
Identified Species:
37.5
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S626
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Chimpanzee
Pan troglodytes
XP_513131
442
49225
S422
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S627
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Dog
Lupus familis
XP_532604
646
71462
S626
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S611
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Rat
Rattus norvegicus
Q9R011
615
68782
S596
H
L
R
Q
L
G
C
S
P
D
L
R
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
C774
T
T
L
L
I
S
G
C
S
L
E
L
K
N
R
Chicken
Gallus gallus
XP_422425
639
71988
S619
S
I
Q
E
L
G
C
S
P
E
L
Q
H
C
L
Frog
Xenopus laevis
P70032
598
68193
A577
L
A
S
R
L
R
Y
A
R
T
M
V
E
K
L
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
G622
L
N
V
L
S
E
L
G
C
S
P
E
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
Y557
N
G
V
S
K
D
L
Y
Q
K
I
R
Y
A
Q
Honey Bee
Apis mellifera
XP_396707
575
66141
K556
G
C
C
K
G
L
A
K
N
L
A
Y
A
H
E
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
L607
P
A
A
N
A
V
R
L
P
S
T
S
S
N
V
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
V568
I
K
Y
A
N
N
M
V
K
N
M
L
D
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
N607
D
R
T
E
I
I
L
N
S
E
N
K
Q
V
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
V420
R
P
S
L
K
D
I
V
W
K
W
Q
G
N
N
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
P677
V
L
K
Y
G
E
I
P
G
Y
P
E
S
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
46.6
13.3
6.6
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
80
46.6
6.6
N.A.
20
6.6
13.3
20
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
6
6
6
0
6
6
0
0
6
0
6
6
0
% A
% Cys:
0
6
6
0
0
0
42
6
6
0
0
0
0
6
0
% C
% Asp:
6
0
0
0
0
12
0
0
0
36
0
0
6
0
0
% D
% Glu:
0
0
0
12
0
12
0
0
0
12
6
12
6
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
6
6
0
0
12
42
6
6
6
0
0
0
6
0
0
% G
% His:
36
0
0
0
0
0
0
0
0
0
0
0
6
6
0
% H
% Ile:
6
6
0
0
12
6
12
0
0
0
6
0
0
0
0
% I
% Lys:
0
6
6
6
12
0
0
6
6
12
0
6
6
12
6
% K
% Leu:
12
42
6
18
48
6
18
6
0
12
42
12
6
0
48
% L
% Met:
0
0
0
0
0
0
6
0
0
0
12
0
0
0
0
% M
% Asn:
6
6
0
6
6
6
0
6
6
6
6
0
0
24
6
% N
% Pro:
6
6
0
0
0
0
0
6
48
0
12
0
0
0
0
% P
% Gln:
0
0
6
36
0
0
0
0
6
0
0
12
42
0
12
% Q
% Arg:
6
6
36
6
0
6
6
0
6
0
0
42
0
42
6
% R
% Ser:
6
0
12
6
6
6
0
42
12
12
0
6
12
0
0
% S
% Thr:
6
6
6
0
0
0
0
0
0
6
6
0
0
0
6
% T
% Val:
6
0
12
0
0
6
0
12
0
0
0
6
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% W
% Tyr:
0
0
6
6
0
0
6
6
0
6
0
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _