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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
21.82
Human Site:
S515
Identified Species:
30
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S515
P
T
S
T
K
H
F
S
F
S
V
G
A
V
P
Chimpanzee
Pan troglodytes
XP_513131
442
49225
M316
L
R
N
C
V
A
F
M
P
P
A
E
Q
N
P
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S516
P
T
S
T
K
H
F
S
F
S
V
G
A
V
P
Dog
Lupus familis
XP_532604
646
71462
S515
P
T
S
T
K
H
F
S
F
S
V
G
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S500
P
T
S
T
K
H
F
S
F
S
M
G
S
V
P
Rat
Rattus norvegicus
Q9R011
615
68782
S485
P
T
S
T
K
H
F
S
F
S
V
G
S
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
V664
A
E
L
G
Q
C
S
V
F
P
A
T
D
A
P
Chicken
Gallus gallus
XP_422425
639
71988
A508
P
T
N
S
K
H
F
A
F
P
V
S
A
V
P
Frog
Xenopus laevis
P70032
598
68193
K469
Y
P
T
T
L
T
K
K
I
T
L
L
K
Y
F
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
S512
L
T
N
N
K
H
F
S
F
P
A
N
A
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
K451
M
T
T
T
D
Y
C
K
S
L
D
K
K
M
K
Honey Bee
Apis mellifera
XP_396707
575
66141
E450
T
V
K
E
Y
P
S
E
L
E
K
K
M
R
L
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
N483
K
Y
F
R
S
Y
M
N
D
H
L
L
Q
A
G
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
Y462
K
K
V
T
L
L
K
Y
F
R
N
Y
M
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
G485
Y
S
S
K
Y
G
M
G
Y
N
L
S
N
G
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
G314
L
I
S
S
L
S
Q
G
F
D
L
S
G
L
F
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
W565
S
Y
D
D
R
E
G
W
V
A
S
H
Y
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
13.3
100
100
N.A.
86.6
93.3
N.A.
13.3
66.6
6.6
53.3
N.A.
13.3
0
0
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
20
86.6
26.6
66.6
N.A.
33.3
0
20
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
6
0
6
0
6
18
0
30
12
0
% A
% Cys:
0
0
0
6
0
6
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
6
6
0
0
0
6
6
6
0
6
0
0
% D
% Glu:
0
6
0
6
0
6
0
6
0
6
0
6
0
0
6
% E
% Phe:
0
0
6
0
0
0
48
0
59
0
0
0
0
0
12
% F
% Gly:
0
0
0
6
0
6
6
12
0
0
0
30
6
6
6
% G
% His:
0
0
0
0
0
42
0
0
0
6
0
6
0
0
0
% H
% Ile:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% I
% Lys:
12
6
6
6
42
0
12
12
0
0
6
12
12
0
6
% K
% Leu:
18
0
6
0
18
6
0
0
6
6
24
12
0
18
12
% L
% Met:
6
0
0
0
0
0
12
6
0
0
6
0
12
6
0
% M
% Asn:
0
0
18
6
0
0
0
6
0
6
6
6
6
6
0
% N
% Pro:
36
6
0
0
0
6
0
0
6
24
0
0
0
0
53
% P
% Gln:
0
0
0
0
6
0
6
0
0
0
0
0
12
0
0
% Q
% Arg:
0
6
0
6
6
0
0
0
0
6
0
0
0
6
0
% R
% Ser:
6
6
42
12
6
6
12
36
6
30
6
18
12
6
0
% S
% Thr:
6
48
12
48
0
6
0
0
0
6
0
6
0
0
6
% T
% Val:
0
6
6
0
6
0
0
6
6
0
30
0
0
36
0
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
12
12
0
6
6
0
0
6
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _