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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
20.3
Human Site:
S298
Identified Species:
27.92
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S298
L
A
A
I
L
R
A
S
P
R
D
R
P
S
I
Chimpanzee
Pan troglodytes
XP_513131
442
49225
S115
G
P
E
A
D
V
W
S
L
G
C
V
M
Y
T
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S298
L
A
A
I
L
R
A
S
P
R
D
R
P
S
I
Dog
Lupus familis
XP_532604
646
71462
S298
L
A
A
I
L
R
A
S
P
Q
D
R
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S299
L
A
A
I
L
R
A
S
P
R
D
R
P
S
I
Rat
Rattus norvegicus
Q9R011
615
68782
S267
L
A
A
I
L
R
A
S
P
R
D
R
P
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
N427
I
A
S
M
L
S
K
N
P
E
D
R
P
R
L
Chicken
Gallus gallus
XP_422425
639
71988
N282
I
A
G
I
L
K
R
N
P
Q
D
R
L
T
L
Frog
Xenopus laevis
P70032
598
68193
A269
P
K
H
I
N
P
V
A
A
A
L
I
Q
K
M
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
N279
I
S
S
I
L
Q
K
N
P
C
D
R
L
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
A251
S
Y
L
R
K
P
A
A
D
M
V
I
A
M
L
Honey Bee
Apis mellifera
XP_396707
575
66141
N250
H
I
N
T
I
A
M
N
M
I
S
N
M
L
Q
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
V271
I
R
V
L
L
D
P
V
P
S
R
R
P
N
A
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
L259
A
R
N
L
I
V
K
L
L
K
N
D
P
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
T273
N
L
V
Q
K
M
L
T
L
D
P
S
K
R
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Y114
K
E
N
I
A
R
K
Y
F
Q
Q
L
I
G
A
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S319
I
L
I
R
D
I
L
S
L
D
P
I
E
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
6.6
100
93.3
N.A.
100
100
N.A.
40
40
6.6
33.3
N.A.
6.6
0
26.6
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
73.3
80
20
80
N.A.
20
13.3
46.6
40
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
42
30
6
6
6
36
12
6
6
0
0
6
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
6
0
0
0
0
% C
% Asp:
0
0
0
0
12
6
0
0
6
12
48
6
0
0
0
% D
% Glu:
0
6
6
0
0
0
0
0
0
6
0
0
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
6
0
6
0
0
0
0
0
0
6
0
0
0
6
0
% G
% His:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
6
6
53
12
6
0
0
0
6
0
18
6
0
30
% I
% Lys:
6
6
0
0
12
6
24
0
0
6
0
0
6
6
0
% K
% Leu:
30
12
6
12
53
0
12
6
24
0
6
6
12
6
24
% L
% Met:
0
0
0
6
0
6
6
0
6
6
0
0
12
6
6
% M
% Asn:
6
0
18
0
6
0
0
24
0
0
6
6
0
6
0
% N
% Pro:
6
6
0
0
0
12
6
0
53
0
12
0
48
0
12
% P
% Gln:
0
0
0
6
0
6
0
0
0
18
6
0
6
0
12
% Q
% Arg:
0
12
0
12
0
36
6
0
0
24
6
53
0
18
0
% R
% Ser:
6
6
12
0
0
6
0
42
0
6
6
6
0
30
0
% S
% Thr:
0
0
0
6
0
0
0
6
0
0
0
0
0
18
6
% T
% Val:
0
0
12
0
0
12
6
6
0
0
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
6
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _