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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNPEP
All Species:
26.67
Human Site:
Y491
Identified Species:
48.89
UniProt:
Q9H4A4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4A4
NP_064601.3
650
72596
Y491
N
T
P
G
W
P
P
Y
L
P
D
L
S
P
G
Chimpanzee
Pan troglodytes
XP_001149557
650
72508
Y491
N
T
P
G
W
P
P
Y
L
P
D
L
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001107559
650
72476
Y491
N
T
P
G
W
P
P
Y
L
P
D
L
S
P
G
Dog
Lupus familis
XP_547357
650
72248
Y491
N
S
P
G
W
P
P
Y
L
P
D
L
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCT3
650
72325
Y491
N
T
P
G
W
P
P
Y
L
P
D
L
S
P
G
Rat
Rattus norvegicus
O09175
650
72601
Y491
N
T
P
G
W
P
P
Y
L
P
D
L
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509819
759
84771
V605
H
S
P
G
M
P
P
V
K
P
K
Y
D
M
T
Chicken
Gallus gallus
XP_419245
628
70471
F468
N
T
P
G
W
P
P
F
L
P
D
L
S
P
G
Frog
Xenopus laevis
NP_001087880
612
69620
F456
N
T
P
G
W
P
P
F
L
P
D
L
S
P
G
Zebra Danio
Brachydanio rerio
NP_001002741
626
71245
Y471
N
V
P
G
W
P
P
Y
V
P
D
L
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793744
583
65836
K455
Y
H
K
E
K
D
N
K
D
L
S
L
D
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q10740
671
77334
R502
Y
K
P
G
M
P
P
R
P
H
F
I
T
A
L
Red Bread Mold
Neurospora crassa
Q7S785
614
68982
P461
S
T
G
L
P
P
K
P
E
F
D
T
S
L
A
Conservation
Percent
Protein Identity:
100
99
98.3
88.7
N.A.
88.9
88.4
N.A.
32.5
67.5
64.7
62
N.A.
N.A.
N.A.
N.A.
49.8
Protein Similarity:
100
99.3
99
94
N.A.
94.3
94
N.A.
48
79.3
77.8
76.1
N.A.
N.A.
N.A.
N.A.
67.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
33.3
93.3
93.3
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
46.6
100
100
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.2
32.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
51
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
77
0
16
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
8
8
0
0
0
0
% F
% Gly:
0
0
8
85
0
0
0
0
0
0
0
0
0
0
70
% G
% His:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
8
8
0
8
0
8
8
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
62
8
0
77
0
8
8
% L
% Met:
0
0
0
0
16
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
70
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
85
0
8
93
85
8
8
77
0
0
0
62
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
16
0
0
0
0
0
0
0
0
8
0
77
0
8
% S
% Thr:
0
62
0
0
0
0
0
0
0
0
0
8
8
0
8
% T
% Val:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _