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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA6B
All Species:
12.73
Human Site:
T722
Identified Species:
28
UniProt:
Q9H3T3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3T3
NP_115484.2
888
95285
T722
L
P
Q
K
R
L
P
T
P
H
P
H
P
H
A
Chimpanzee
Pan troglodytes
XP_001139016
877
93643
T711
L
P
Q
K
R
L
P
T
P
H
P
H
P
H
A
Rhesus Macaque
Macaca mulatta
XP_001112417
998
111576
Q711
V
L
H
Q
K
T
L
Q
A
M
K
S
H
S
E
Dog
Lupus familis
XP_542153
673
73761
L524
V
G
T
V
L
K
F
L
I
W
P
N
A
S
T
Cat
Felis silvestris
Mouse
Mus musculus
O54951
886
95448
T723
L
P
Q
K
R
L
P
T
P
H
P
H
A
H
A
Rat
Rattus norvegicus
O70141
887
95734
T723
L
P
Q
K
R
L
P
T
T
H
P
H
A
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513097
932
103818
P770
T
L
Q
Q
K
R
K
P
S
R
G
S
R
E
W
Chicken
Gallus gallus
Q90607
772
88849
K623
D
D
H
K
V
E
I
K
V
D
D
R
M
I
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W686
778
88886
R629
L
E
I
K
S
D
E
R
V
L
G
T
E
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
N657
E
Y
F
E
Q
R
Q
N
V
N
S
F
P
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17330
712
78063
A563
F
D
D
N
E
S
E
A
Q
P
E
A
V
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
39.2
62.3
N.A.
89.5
89
N.A.
44.4
26
N.A.
26.5
N.A.
28.3
N.A.
26.4
N.A.
Protein Similarity:
100
94.8
54.2
65.1
N.A.
92.1
91.7
N.A.
58.4
42.3
N.A.
43.3
N.A.
43.4
N.A.
42.3
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
93.3
86.6
N.A.
6.6
6.6
N.A.
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
20
20
N.A.
93.3
86.6
N.A.
20
6.6
N.A.
13.3
N.A.
33.3
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
10
28
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
10
0
0
10
0
0
0
10
10
0
0
0
0
% D
% Glu:
10
10
0
10
10
10
19
0
0
0
10
0
10
10
10
% E
% Phe:
10
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
19
0
0
0
10
% G
% His:
0
0
19
0
0
0
0
0
0
37
0
37
10
37
0
% H
% Ile:
0
0
10
0
0
0
10
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
55
19
10
10
10
0
0
10
0
0
0
0
% K
% Leu:
46
19
0
0
10
37
10
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
0
37
0
0
0
0
37
10
28
10
46
0
28
0
0
% P
% Gln:
0
0
46
19
10
0
10
10
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
37
19
0
10
0
10
0
10
10
0
19
% R
% Ser:
0
0
0
0
10
10
0
0
10
0
10
19
0
37
10
% S
% Thr:
10
0
10
0
0
10
0
37
10
0
0
10
0
0
10
% T
% Val:
19
0
0
10
10
0
0
0
28
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _