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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WHSC2 All Species: 27.58
Human Site: S321 Identified Species: 50.56
UniProt: Q9H3P2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3P2 NP_005654.3 528 57277 S321 N N E P A L P S T S Y L P S T
Chimpanzee Pan troglodytes XP_517069 544 59069 S337 N N E P A L P S T S Y L P S T
Rhesus Macaque Macaca mulatta XP_001100646 528 57235 S321 N S E P A L P S T S Y L P S T
Dog Lupus familis XP_545924 532 57508 L325 A L P S T S Y L P A T P S V V
Cat Felis silvestris
Mouse Mus musculus Q8BG30 530 57567 S321 N S E P T L P S T S Y L P S T
Rat Rattus norvegicus NP_001008340 530 57523 S321 N S E P T L P S T S Y L P S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521065 458 48855 Y254 P A L P S T S Y L P A A P S A
Chicken Gallus gallus NP_001026338 539 58976 S335 N N E P A L P S T S Y L P A T
Frog Xenopus laevis NP_001087790 358 38995 E154 K S A T L R A E L L Q K S T E
Zebra Danio Brachydanio rerio NP_001166972 542 58457 S320 N N E S A L P S T S Y L P A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q86NP2 1251 134931 Q595 Q P Q T L Q V Q Q A P Q Q S H
Honey Bee Apis mellifera XP_392087 527 57730 P321 Q G L T S I N P P A T P I T P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793990 211 23796
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 98.8 94.9 N.A. 95.4 95.4 N.A. 58.7 84.7 59.2 80.6 N.A. 23.2 44.8 N.A. 21.9
Protein Similarity: 100 97 99.4 95.8 N.A. 96.7 96.7 N.A. 65.7 89.9 64.1 85.7 N.A. 31.3 61.5 N.A. 30.3
P-Site Identity: 100 100 93.3 0 N.A. 86.6 86.6 N.A. 20 93.3 0 86.6 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 26.6 100 13.3 93.3 N.A. 20 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 39 0 8 0 0 24 8 8 0 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 54 0 0 0 0 8 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 8 16 0 16 54 0 8 16 8 0 54 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 54 31 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 54 0 0 54 8 16 8 8 16 62 0 8 % P
% Gln: 16 0 8 0 0 8 0 8 8 0 8 8 8 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 31 0 16 16 8 8 54 0 54 0 0 16 54 0 % S
% Thr: 0 0 0 24 24 8 0 0 54 0 16 0 0 16 54 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 0 0 54 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _