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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX1
All Species:
15.45
Human Site:
S221
Identified Species:
34
UniProt:
Q9H3N1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3N1
NP_110382.3
280
31791
S221
P
Q
P
Y
P
Y
P
S
K
K
L
L
S
E
S
Chimpanzee
Pan troglodytes
XP_522851
280
31687
S221
P
Q
P
Y
P
Y
P
S
K
K
L
L
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001102891
280
31816
S221
P
Q
P
Y
P
Y
P
S
K
K
L
L
S
E
S
Dog
Lupus familis
XP_853432
392
44456
S333
R
R
P
Q
P
Y
P
S
K
K
L
L
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBT0
278
31377
A219
R
K
P
Q
Q
Q
Y
A
K
K
T
S
P
E
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515290
285
32557
K228
P
Q
Q
Y
P
Y
S
K
K
I
P
P
E
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108605
284
32319
L228
P
D
Y
H
H
R
K
L
P
A
R
Q
V
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611838
323
36326
Q228
R
Q
S
F
S
E
S
Q
D
N
L
T
E
G
L
Honey Bee
Apis mellifera
XP_397478
291
33381
S228
K
K
K
Q
K
E
G
S
G
G
F
M
Q
E
K
Nematode Worm
Caenorhab. elegans
Q17967
485
53418
L291
A
K
I
V
F
V
L
L
D
V
D
V
E
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
S282
A
K
Y
T
G
G
A
S
L
A
E
V
A
E
E
Conservation
Percent
Protein Identity:
100
98.9
97.8
66.5
N.A.
77.5
N.A.
N.A.
75.7
N.A.
N.A.
52.8
N.A.
38
38.4
21
N.A.
Protein Similarity:
100
99.6
98.2
69.6
N.A.
85.7
N.A.
N.A.
85.6
N.A.
N.A.
66.5
N.A.
55.4
58.4
35.4
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
26.6
N.A.
N.A.
40
N.A.
N.A.
6.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
40
N.A.
N.A.
46.6
N.A.
N.A.
13.3
N.A.
20
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
10
10
0
19
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
0
10
0
0
0
0
0
0
19
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
10
0
28
73
10
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
0
0
0
10
10
10
0
10
10
0
0
0
10
0
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
37
10
0
10
0
10
10
55
46
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
10
19
10
0
46
37
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
46
0
46
0
46
0
37
0
10
0
10
10
19
0
0
% P
% Gln:
0
46
10
28
10
10
0
10
0
0
0
10
10
0
0
% Q
% Arg:
28
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
19
55
0
0
0
10
28
10
37
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
10
% T
% Val:
0
0
0
10
0
10
0
0
0
10
0
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
37
0
46
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _