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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMADHC
All Species:
35.76
Human Site:
Y140
Identified Species:
78.67
UniProt:
Q9H3L0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3L0
NP_056517.1
296
32940
Y140
E
I
N
S
A
E
T
Y
F
E
S
A
R
V
E
Chimpanzee
Pan troglodytes
XP_001135225
330
36302
Y140
E
I
N
S
A
E
T
Y
F
E
S
A
R
V
E
Rhesus Macaque
Macaca mulatta
XP_001082098
296
32978
Y140
E
I
N
S
A
E
T
Y
F
E
S
A
R
V
E
Dog
Lupus familis
XP_849074
298
33300
Y140
E
I
S
S
A
E
T
Y
F
E
N
A
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99LS1
296
32977
Y140
E
I
N
S
A
E
T
Y
F
E
S
A
K
V
E
Rat
Rattus norvegicus
Q6AYQ6
296
33034
Y140
E
I
S
S
A
E
T
Y
F
E
S
A
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510005
457
50420
Y202
E
I
N
S
A
E
M
Y
F
E
N
A
K
V
E
Chicken
Gallus gallus
Q5ZKP2
296
33113
Y140
Q
V
N
N
A
E
T
Y
F
E
N
A
K
V
E
Frog
Xenopus laevis
NP_001089489
297
33362
Y141
E
L
N
T
I
E
S
Y
F
E
N
A
K
V
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572537
284
31746
F125
P
L
G
H
L
V
N
F
H
K
G
P
N
T
D
Honey Bee
Apis mellifera
XP_624068
306
34815
C128
T
R
H
S
M
L
H
C
V
A
Q
E
C
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.6
98.6
92.6
N.A.
93.5
92.9
N.A.
55.1
83.4
73
N.A.
N.A.
22.6
29.4
N.A.
N.A.
Protein Similarity:
100
89.6
99.6
95.9
N.A.
97.6
97.3
N.A.
60.3
91.8
86.5
N.A.
N.A.
36.8
46.4
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
80
66.6
60
N.A.
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
93.3
N.A.
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
73
0
0
0
0
10
0
82
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
73
0
0
0
0
82
0
0
0
82
0
10
0
0
82
% E
% Phe:
0
0
0
0
0
0
0
10
82
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
10
10
0
0
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
64
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
46
0
0
% K
% Leu:
0
19
0
0
10
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
64
10
0
0
10
0
0
0
37
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
37
0
0
% R
% Ser:
0
0
19
73
0
0
10
0
0
0
46
0
0
0
0
% S
% Thr:
10
0
0
10
0
0
64
0
0
0
0
0
0
10
0
% T
% Val:
0
10
0
0
0
10
0
0
10
0
0
0
0
82
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _