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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNX25
All Species:
25.76
Human Site:
Y356
Identified Species:
51.52
UniProt:
Q9H3E2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3E2
NP_114159.2
840
97945
Y356
I
S
V
E
K
S
L
Y
K
E
I
Q
Q
C
L
Chimpanzee
Pan troglodytes
XP_517558
840
97813
Y356
I
S
V
E
K
S
L
Y
K
E
I
Q
Q
C
L
Rhesus Macaque
Macaca mulatta
XP_001088124
206
24304
Dog
Lupus familis
XP_532843
840
98054
Y356
I
S
V
E
K
S
L
Y
K
E
I
Q
Q
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3ZT31
846
97681
Y362
I
S
V
E
K
S
L
Y
K
E
I
Q
Q
C
L
Rat
Rattus norvegicus
XP_224863
840
97156
Y356
I
P
V
E
K
S
L
Y
K
E
I
Q
Q
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517135
496
56408
D70
F
I
V
S
D
I
Y
D
K
L
L
K
T
E
E
Chicken
Gallus gallus
XP_420506
839
97470
Y356
I
P
V
E
K
S
L
Y
K
E
I
E
Q
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001156765
961
110753
Y482
I
P
V
E
K
A
L
Y
K
E
I
Q
Q
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572421
1117
125178
Q508
P
D
I
F
Y
D
I
Q
R
N
V
L
R
T
L
Honey Bee
Apis mellifera
XP_001123040
913
105547
R453
I
K
I
D
R
T
I
R
K
R
M
E
S
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788218
1003
114275
K455
V
G
T
S
S
V
V
K
V
E
R
Q
L
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
20.9
95
N.A.
86.2
88.3
N.A.
42.8
81.5
N.A.
63.7
N.A.
26.5
34
N.A.
32.5
Protein Similarity:
100
99.6
23.1
97.3
N.A.
91.8
94.1
N.A.
50.7
90.4
N.A.
76
N.A.
44.4
56.7
N.A.
49.4
P-Site Identity:
100
100
0
100
N.A.
100
93.3
N.A.
13.3
80
N.A.
80
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
0
100
N.A.
100
93.3
N.A.
26.6
86.6
N.A.
86.6
N.A.
40
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% C
% Asp:
0
9
0
9
9
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
59
0
0
0
0
0
67
0
17
0
9
9
% E
% Phe:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
9
17
0
0
9
17
0
0
0
59
0
0
9
0
% I
% Lys:
0
9
0
0
59
0
0
9
75
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
0
59
0
0
9
9
9
9
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
59
59
0
0
% Q
% Arg:
0
0
0
0
9
0
0
9
9
9
9
0
9
0
9
% R
% Ser:
0
34
0
17
9
50
0
0
0
0
0
0
9
9
0
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
9
17
0
% T
% Val:
9
0
67
0
0
9
9
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _