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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIPK2 All Species: 18.18
Human Site: Y361 Identified Species: 44.44
UniProt: Q9H2X6 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2X6 NP_001106710.1 1198 130966 Y361 S K A V C S T Y L Q S R Y Y R
Chimpanzee Pan troglodytes XP_001152004 1191 130183 R358 C S T Y L Q S R Y Y R A P E I
Rhesus Macaque Macaca mulatta XP_001106719 1195 130693 Y386 S K A V C S T Y L Q S R Y Y R
Dog Lupus familis XP_856178 1158 125632 R356 C S T Y L Q S R Y Y R A P E I
Cat Felis silvestris
Mouse Mus musculus Q9QZR5 1196 130480 Y361 S K A V C S T Y L Q S R Y Y R
Rat Rattus norvegicus A4L9P5 1211 130782 R356 C S T Y L Q S R Y Y R A P E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416335 1203 131231 Y359 S K A V C S T Y L Q S R Y Y R
Frog Xenopus laevis Q2TAE3 750 84138
Zebra Danio Brachydanio rerio NP_001073629 1226 133548 Y375 S K A V C S T Y L Q S R Y Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49657 908 95884 H110 D L I K T Y K H I N E V Y Y A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.9 65.4 N.A. 96.7 60.8 N.A. N.A. 92.9 23.4 80 N.A. 22 N.A. N.A. N.A.
Protein Similarity: 100 99.3 97.2 76.3 N.A. 98 71.9 N.A. N.A. 95.4 35.7 85.8 N.A. 37.3 N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 100 0 N.A. N.A. 100 0 100 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 6.6 N.A. 100 6.6 N.A. N.A. 100 0 100 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 0 0 0 0 0 0 30 0 0 10 % A
% Cys: 30 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 30 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 30 % I
% Lys: 0 50 0 10 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 30 0 0 0 50 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 % P
% Gln: 0 0 0 0 0 30 0 0 0 50 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 30 0 0 30 50 0 0 50 % R
% Ser: 50 30 0 0 0 50 30 0 0 0 50 0 0 0 0 % S
% Thr: 0 0 30 0 10 0 50 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 50 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 30 0 10 0 50 30 30 0 0 60 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _