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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRD All Species: 17.58
Human Site: S777 Identified Species: 35.15
UniProt: Q9H2X0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2X0 NP_003732.2 955 102032 S777 D L P G L P R S R D P G E G C
Chimpanzee Pan troglodytes XP_516917 1220 131139 S777 D L P G L P R S R D P G E G C
Rhesus Macaque Macaca mulatta XP_001097729 955 102155 S777 D L P G L P R S R D P G E G C
Dog Lupus familis XP_849776 959 101663 T782 D L P G L S R T R D P G E G C
Cat Felis silvestris
Mouse Mus musculus Q9Z0E2 948 101495 N772 R D L P S L P N L E P G E G C
Rat Rattus norvegicus Q63148 951 101988 N775 R D L P S L P N L E P G E G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518867 1007 107733 S797 V R E G L D Q S R D P G E G C
Chicken Gallus gallus
Frog Xenopus laevis Q91713 941 104929 R764 R E V K K P E R A R T S E G C
Zebra Danio Brachydanio rerio O57472 940 104981 V762 E T A A V E K V E E N P E G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24025 1038 115496 T823 S S P A T N A T D L L Q Q R R
Honey Bee Apis mellifera XP_393520 940 104011 P716 P A P G H C C P I C S G P G I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001103715 969 106349 E780 C P S C P K P E E P E E P G C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 96.7 92.2 N.A. 86 85.3 N.A. 72.5 N.A. 50.7 47.6 N.A. 26.9 28.8 N.A. 33.9
Protein Similarity: 100 78.1 97.4 94.7 N.A. 89.7 89.3 N.A. 80.2 N.A. 67.5 65 N.A. 42 42.5 N.A. 51.2
P-Site Identity: 100 100 100 86.6 N.A. 33.3 33.3 N.A. 66.6 N.A. 26.6 20 N.A. 6.6 26.6 N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 46.6 46.6 N.A. 73.3 N.A. 26.6 46.6 N.A. 20 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 17 0 0 9 0 9 0 0 0 0 0 0 % A
% Cys: 9 0 0 9 0 9 9 0 0 9 0 0 0 0 84 % C
% Asp: 34 17 0 0 0 9 0 0 9 42 0 0 0 0 0 % D
% Glu: 9 9 9 0 0 9 9 9 17 25 9 9 75 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 0 0 0 67 0 92 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % I
% Lys: 0 0 0 9 9 9 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 34 17 0 42 17 0 0 17 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 17 0 0 9 0 0 0 0 % N
% Pro: 9 9 50 17 9 34 25 9 0 9 59 9 17 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 9 9 0 0 % Q
% Arg: 25 9 0 0 0 0 34 9 42 9 0 0 0 9 9 % R
% Ser: 9 9 9 0 17 9 0 34 0 0 9 9 0 0 0 % S
% Thr: 0 9 0 0 9 0 0 17 0 0 9 0 0 0 0 % T
% Val: 9 0 9 0 9 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _