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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPNS1
All Species:
17.27
Human Site:
T506
Identified Species:
38
UniProt:
Q9H2V7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2V7
NP_001135923.1
528
56630
T506
L
L
H
E
A
G
S
T
D
D
R
I
V
V
P
Chimpanzee
Pan troglodytes
XP_001147063
528
56585
T506
L
L
H
E
A
G
S
T
D
D
R
I
V
V
P
Rhesus Macaque
Macaca mulatta
XP_001102328
528
56547
T506
L
L
H
E
A
G
P
T
D
D
Q
I
V
V
P
Dog
Lupus familis
XP_850001
528
56636
A506
L
L
R
E
A
G
P
A
D
D
R
I
V
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0G7
528
56690
S506
L
L
H
E
S
G
P
S
D
D
R
I
V
V
P
Rat
Rattus norvegicus
Q2YDU8
528
56778
S506
L
L
H
E
T
E
P
S
D
D
Q
I
V
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415740
403
43745
G382
C
P
F
V
V
V
L
G
G
M
F
F
L
A
T
Frog
Xenopus laevis
Q5XGK0
526
57788
D504
L
L
P
A
D
E
T
D
A
E
R
I
V
V
P
Zebra Danio
Brachydanio rerio
Q7ZU13
506
54962
D484
A
E
N
Y
V
P
S
D
D
A
P
I
V
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GQQ0
605
65801
A584
I
I
K
D
K
Y
N
A
T
R
G
L
Q
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193605
553
60509
T532
D
D
K
K
R
V
Q
T
I
V
S
N
E
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.4
95.6
N.A.
93.5
93.3
N.A.
N.A.
44.8
66.2
65.5
N.A.
42.4
N.A.
N.A.
45
Protein Similarity:
100
99.8
98.6
97.5
N.A.
96
95.6
N.A.
N.A.
54.7
81
76.3
N.A.
56.8
N.A.
N.A.
63.6
P-Site Identity:
100
100
86.6
80
N.A.
80
66.6
N.A.
N.A.
0
46.6
40
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
80
N.A.
N.A.
6.6
60
46.6
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
37
0
0
19
10
10
0
0
0
10
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
10
0
0
19
64
55
0
0
0
10
0
% D
% Glu:
0
10
0
55
0
19
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
46
0
10
10
0
10
0
0
0
0
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
10
0
0
73
0
0
0
% I
% Lys:
0
0
19
10
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
64
0
0
0
0
10
0
0
0
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
10
0
0
10
37
0
0
0
10
0
0
0
73
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
19
0
10
0
0
% Q
% Arg:
0
0
10
0
10
0
0
0
0
10
46
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
28
19
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
37
10
0
0
0
0
0
10
% T
% Val:
0
0
0
10
19
19
0
0
0
10
0
0
73
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _