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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPNS1
All Species:
36.97
Human Site:
S442
Identified Species:
81.33
UniProt:
Q9H2V7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2V7
NP_001135923.1
528
56630
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
N
W
Chimpanzee
Pan troglodytes
XP_001147063
528
56585
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
N
W
Rhesus Macaque
Macaca mulatta
XP_001102328
528
56547
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
N
W
Dog
Lupus familis
XP_850001
528
56636
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0G7
528
56690
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
S
W
Rat
Rattus norvegicus
Q2YDU8
528
56778
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415740
403
43745
Q330
R
A
T
A
V
A
L
Q
S
F
T
S
H
L
L
Frog
Xenopus laevis
Q5XGK0
526
57788
S440
P
Y
L
I
G
V
I
S
D
Q
I
Q
K
G
K
Zebra Danio
Brachydanio rerio
Q7ZU13
506
54962
S429
P
Y
L
I
G
V
V
S
D
S
I
K
E
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GQQ0
605
65801
S486
P
Y
L
V
G
A
I
S
E
A
I
M
K
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193605
553
60509
S478
P
W
L
V
G
A
V
S
D
S
I
R
N
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.4
95.6
N.A.
93.5
93.3
N.A.
N.A.
44.8
66.2
65.5
N.A.
42.4
N.A.
N.A.
45
Protein Similarity:
100
99.8
98.6
97.5
N.A.
96
95.6
N.A.
N.A.
54.7
81
76.3
N.A.
56.8
N.A.
N.A.
63.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
53.3
46.6
N.A.
40
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
86.6
80
N.A.
73.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
28
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
91
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% H
% Ile:
0
0
0
73
0
0
73
0
0
0
37
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
10
% K
% Leu:
0
0
91
0
0
55
10
0
0
0
55
0
0
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
28
10
% N
% Pro:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
55
0
64
55
0
0
% R
% Ser:
0
0
0
0
0
0
0
91
10
19
0
10
0
46
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
19
10
19
19
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
55
% W
% Tyr:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _