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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPC1 All Species: 14.55
Human Site: S487 Identified Species: 29.09
UniProt: Q9H2F5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2F5 NP_079485.1 836 93463 S487 H L D L E M L S S P Q H S P V
Chimpanzee Pan troglodytes XP_507733 842 94267 S487 H L D L E M L S S P Q H S P V
Rhesus Macaque Macaca mulatta XP_001091098 681 77941 P353 P S S A A A A P Q Q T S P A A
Dog Lupus familis XP_535156 842 94080 S487 H L D L E M L S S P Q H S P V
Cat Felis silvestris
Mouse Mus musculus Q8C9X6 813 90392 L482 S M F H H L D L D M L S S P Q
Rat Rattus norvegicus NP_001102051 808 90800 I477 H D P V L K Q I D P E M L N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509590 778 87501 Q445 T E H D P V L Q Q L D P E M L
Chicken Gallus gallus XP_418573 843 94228 S487 Q L D L E M L S S S Q H S S I
Frog Xenopus laevis Q66JA8 804 90630 S472 R L S T E H D S V L K Q I D P
Zebra Danio Brachydanio rerio NP_001082878 797 88820 T465 R A H S E W D T V Y H G L D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397232 868 96064 F509 V K K E W L H F R P K T P P V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192895 443 51775 D115 E Q D I P D Y D M D S G D E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 80.3 97.2 N.A. 90.5 53.9 N.A. 48.9 92.6 54 64.3 N.A. N.A. 35.1 N.A. 30.9
Protein Similarity: 100 97.6 80.7 98.2 N.A. 93.9 68.7 N.A. 62.6 95.9 67.4 75.7 N.A. N.A. 51 N.A. 41
P-Site Identity: 100 100 0 100 N.A. 13.3 13.3 N.A. 6.6 73.3 20 6.6 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 100 100 0 100 N.A. 26.6 26.6 N.A. 20 80 26.6 13.3 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 9 9 9 0 0 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 42 9 0 9 25 9 17 9 9 0 9 17 0 % D
% Glu: 9 9 0 9 50 0 0 0 0 0 9 0 9 9 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 9 % G
% His: 34 0 17 9 9 9 9 0 0 0 9 34 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 9 0 0 0 0 9 0 9 % I
% Lys: 0 9 9 0 0 9 0 0 0 0 17 0 0 0 0 % K
% Leu: 0 42 0 34 9 17 42 9 0 17 9 0 17 0 9 % L
% Met: 0 9 0 0 0 34 0 0 9 9 0 9 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 9 0 9 0 17 0 0 9 0 42 0 9 17 42 17 % P
% Gln: 9 9 0 0 0 0 9 9 17 9 34 9 0 0 9 % Q
% Arg: 17 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % R
% Ser: 9 9 17 9 0 0 0 42 34 9 9 17 42 9 0 % S
% Thr: 9 0 0 9 0 0 0 9 0 0 9 9 0 0 0 % T
% Val: 9 0 0 9 0 9 0 0 17 0 0 0 0 0 34 % V
% Trp: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _