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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC1
All Species:
22.12
Human Site:
S427
Identified Species:
44.24
UniProt:
Q9H2F5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2F5
NP_079485.1
836
93463
S427
T
G
N
W
P
W
T
S
P
K
D
G
G
L
G
Chimpanzee
Pan troglodytes
XP_507733
842
94267
S427
T
G
N
W
P
W
T
S
P
K
D
G
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001091098
681
77941
I304
Y
A
I
P
I
I
P
I
T
N
S
S
Q
F
K
Dog
Lupus familis
XP_535156
842
94080
S427
T
G
N
W
P
W
T
S
P
K
D
G
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9X6
813
90392
S426
T
G
N
W
P
W
T
S
P
K
D
G
G
L
G
Rat
Rattus norvegicus
NP_001102051
808
90800
S423
A
N
N
H
P
C
E
S
S
E
L
A
D
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
S393
P
T
S
L
S
Y
E
S
P
E
L
A
D
L
A
Chicken
Gallus gallus
XP_418573
843
94228
S427
P
G
N
W
P
W
S
S
P
K
E
G
R
L
G
Frog
Xenopus laevis
Q66JA8
804
90630
T423
Q
M
N
D
T
P
E
T
T
D
L
S
G
L
A
Zebra Danio
Brachydanio rerio
NP_001082878
797
88820
D416
V
S
G
W
P
W
S
D
P
A
E
G
G
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
D423
F
G
N
W
P
W
C
D
K
N
E
G
G
M
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
G66
I
S
A
Q
Q
V
Y
G
S
A
N
H
L
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
80.3
97.2
N.A.
90.5
53.9
N.A.
48.9
92.6
54
64.3
N.A.
N.A.
35.1
N.A.
30.9
Protein Similarity:
100
97.6
80.7
98.2
N.A.
93.9
68.7
N.A.
62.6
95.9
67.4
75.7
N.A.
N.A.
51
N.A.
41
P-Site Identity:
100
100
0
100
N.A.
100
26.6
N.A.
20
73.3
20
40
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
100
100
0
100
N.A.
100
33.3
N.A.
40
86.6
26.6
60
N.A.
N.A.
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
0
0
0
17
0
17
0
0
34
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
17
0
9
34
0
17
0
9
% D
% Glu:
0
0
0
0
0
0
25
0
0
17
25
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
50
9
0
0
0
0
9
0
0
0
59
59
0
42
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
9
0
9
9
0
9
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
9
42
0
0
0
0
9
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
25
0
9
67
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
67
0
0
0
0
0
0
17
9
0
0
0
0
% N
% Pro:
17
0
0
9
67
9
9
0
59
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
17
9
0
9
0
17
59
17
0
9
17
0
0
0
% S
% Thr:
34
9
0
0
9
0
34
9
17
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
59
0
59
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _