KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX5
All Species:
28.18
Human Site:
S352
Identified Species:
51.67
UniProt:
Q9H2C1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2C1
NP_071758.1
402
44406
S352
I
S
H
P
D
T
P
S
P
E
P
G
L
P
G
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S354
L
A
H
P
P
G
D
S
P
S
P
E
P
S
L
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
S352
I
S
H
P
D
T
P
S
P
E
P
G
L
P
G
Dog
Lupus familis
XP_543409
451
49581
S401
I
S
H
P
D
T
P
S
P
E
P
G
L
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
L338
D
Y
T
V
D
S
N
L
G
I
I
A
H
A
G
Rat
Rattus norvegicus
P61376
402
44369
S352
I
S
H
P
D
T
P
S
P
E
P
G
L
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
E186
F
Q
N
R
R
S
K
E
R
R
M
K
Q
L
S
Chicken
Gallus gallus
P53411
406
44827
S356
H
P
A
G
D
S
P
S
P
E
P
T
L
P
G
Frog
Xenopus laevis
P37137
402
44941
S352
I
S
H
P
D
T
P
S
P
E
P
G
M
T
G
Zebra Danio
Brachydanio rerio
P52889
399
44494
S349
I
S
H
A
D
T
P
S
P
E
P
G
M
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572505
505
54770
Q459
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
N
A
Q
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
A357
N
P
E
T
I
Q
M
A
P
Q
F
A
V
P
T
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
S419
S
G
K
D
M
N
A
S
P
E
P
M
Q
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
99.7
87.3
N.A.
27.8
98.7
N.A.
55.2
73.8
85.3
79
N.A.
41.7
N.A.
40.9
54.1
Protein Similarity:
100
84.4
99.7
87.8
N.A.
46
98.7
N.A.
56.2
84.2
91.5
86.8
N.A.
52.8
N.A.
54.8
62.9
P-Site Identity:
100
33.3
100
100
N.A.
13.3
100
N.A.
0
60
86.6
80
N.A.
0
N.A.
13.3
26.6
P-Site Similarity:
100
46.6
100
100
N.A.
20
100
N.A.
13.3
66.6
93.3
86.6
N.A.
6.6
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
8
8
0
0
0
24
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
62
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
8
0
62
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
0
0
8
0
0
47
0
0
62
% G
% His:
8
0
54
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
47
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
8
0
0
0
0
39
8
16
% L
% Met:
0
0
0
0
8
0
8
0
0
0
8
8
16
0
0
% M
% Asn:
8
0
8
0
0
8
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
16
0
47
8
0
54
0
77
0
70
0
8
47
0
% P
% Gln:
8
16
8
8
8
16
8
8
8
16
0
0
24
8
0
% Q
% Arg:
0
0
0
8
8
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
8
47
0
0
0
24
0
70
0
8
0
0
0
8
8
% S
% Thr:
0
0
8
8
0
47
0
0
0
0
0
8
0
16
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _