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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX5
All Species:
18.18
Human Site:
S268
Identified Species:
33.33
UniProt:
Q9H2C1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2C1
NP_071758.1
402
44406
S268
L
G
G
R
L
D
E
S
E
M
L
G
S
T
P
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
G268
L
V
D
R
L
E
P
G
E
L
I
P
N
G
P
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
S268
L
G
G
R
L
D
E
S
E
M
L
G
S
T
P
Dog
Lupus familis
XP_543409
451
49581
S317
L
G
G
R
L
D
E
S
E
M
L
G
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
S245
S
K
Q
E
K
E
S
S
A
E
D
C
G
V
S
Rat
Rattus norvegicus
P61376
402
44369
S268
L
G
G
R
L
D
E
S
E
M
L
G
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
D108
Q
D
D
P
K
E
T
D
H
S
T
S
S
D
K
Chicken
Gallus gallus
P53411
406
44827
G268
L
V
D
R
L
E
P
G
E
L
L
P
N
G
P
Frog
Xenopus laevis
P37137
402
44941
S268
L
G
G
R
L
D
E
S
E
I
L
S
S
G
P
Zebra Danio
Brachydanio rerio
P52889
399
44494
P268
L
G
G
R
L
E
D
P
D
I
M
G
P
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572505
505
54770
L335
M
N
L
S
P
G
G
L
D
D
G
P
G
F
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
E277
I
R
E
Q
L
A
A
E
T
G
L
N
M
R
V
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
E320
L
R
K
P
F
D
V
E
N
N
P
D
M
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
99.7
87.3
N.A.
27.8
98.7
N.A.
55.2
73.8
85.3
79
N.A.
41.7
N.A.
40.9
54.1
Protein Similarity:
100
84.4
99.7
87.8
N.A.
46
98.7
N.A.
56.2
84.2
91.5
86.8
N.A.
52.8
N.A.
54.8
62.9
P-Site Identity:
100
33.3
100
100
N.A.
6.6
100
N.A.
6.6
40
80
40
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
60
100
100
N.A.
13.3
100
N.A.
13.3
60
86.6
73.3
N.A.
20
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
24
0
0
47
8
8
16
8
8
8
0
8
0
% D
% Glu:
0
0
8
8
0
39
39
16
54
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
47
47
0
0
8
8
16
0
8
8
39
16
31
16
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% I
% Lys:
0
8
8
0
16
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
70
0
8
0
70
0
0
8
0
16
54
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
31
8
0
16
8
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
8
0
8
16
0
0
% N
% Pro:
0
0
0
16
8
0
16
8
0
0
8
24
8
0
62
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
0
62
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
8
0
0
8
47
0
8
0
16
47
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
8
0
0
31
0
% T
% Val:
0
16
0
0
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _