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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX5
All Species:
29.09
Human Site:
S121
Identified Species:
53.33
UniProt:
Q9H2C1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2C1
NP_071758.1
402
44406
S121
V
C
K
D
D
Y
L
S
S
S
S
L
K
E
G
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S120
V
C
K
E
D
Y
L
S
N
S
S
V
A
K
E
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
S121
V
C
K
D
D
Y
L
S
S
S
S
L
K
E
G
Dog
Lupus familis
XP_543409
451
49581
S170
V
C
K
D
D
Y
L
S
S
S
S
L
K
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
P98
A
C
Q
Q
G
I
P
P
T
Q
V
V
R
K
A
Rat
Rattus norvegicus
P61376
402
44369
S121
V
C
K
D
D
Y
L
S
S
S
S
L
K
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
Chicken
Gallus gallus
P53411
406
44827
N120
V
C
K
E
D
Y
L
N
N
S
N
T
A
K
E
Frog
Xenopus laevis
P37137
402
44941
S121
V
C
K
E
D
Y
I
S
A
S
S
L
K
E
S
Zebra Danio
Brachydanio rerio
P52889
399
44494
S121
V
C
K
E
D
Y
L
S
A
S
A
I
K
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572505
505
54770
L143
I
C
K
D
D
Y
L
L
G
K
A
P
S
C
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
R121
L
C
K
T
D
F
S
R
R
Y
S
Q
R
C
A
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
T121
I
C
K
E
D
Y
L
T
K
C
Q
L
R
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
99.7
87.3
N.A.
27.8
98.7
N.A.
55.2
73.8
85.3
79
N.A.
41.7
N.A.
40.9
54.1
Protein Similarity:
100
84.4
99.7
87.8
N.A.
46
98.7
N.A.
56.2
84.2
91.5
86.8
N.A.
52.8
N.A.
54.8
62.9
P-Site Identity:
100
60
100
100
N.A.
6.6
100
N.A.
0
46.6
73.3
66.6
N.A.
46.6
N.A.
26.6
40
P-Site Similarity:
100
86.6
100
100
N.A.
40
100
N.A.
0
80
93.3
93.3
N.A.
60
N.A.
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
16
0
16
0
16
0
16
% A
% Cys:
0
93
0
0
0
0
0
0
0
8
0
0
0
16
0
% C
% Asp:
0
0
0
39
85
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
39
0
0
0
0
0
0
0
0
0
47
16
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
85
0
0
0
0
0
8
8
0
0
47
24
0
% K
% Leu:
8
0
0
0
0
0
70
8
0
0
0
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
16
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
8
% P
% Gln:
0
0
8
8
0
0
0
0
0
8
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
0
24
8
0
% R
% Ser:
0
0
0
0
0
0
8
54
31
62
54
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
8
8
0
0
8
0
0
0
% T
% Val:
62
0
0
0
0
0
0
0
0
0
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
77
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _