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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT4 All Species: 33.94
Human Site: S69 Identified Species: 62.22
UniProt: Q9H2B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2B2 NP_065834.1 425 47958 S69 I Y P E N L N S K K K F G A D
Chimpanzee Pan troglodytes XP_523915 427 48140 S69 I Y P E N L N S K K K F G A D
Rhesus Macaque Macaca mulatta XP_001083607 425 47898 S69 I Y P E N L N S K K K F G A D
Dog Lupus familis XP_547596 425 48163 S69 I Y P E N L S S K K K F G A D
Cat Felis silvestris
Mouse Mus musculus P40749 425 47640 S69 I Y P E N L S S K K K F G G D
Rat Rattus norvegicus P50232 425 47666 S69 I Y P E N L S S K K K F G G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506963 425 47967 S69 I Y P E N L N S K K K F G A D
Chicken Gallus gallus P47191 424 47487 V69 A L I A I A I V A V L L I L T
Frog Xenopus laevis NP_001086261 424 47737 S69 I Y P E S L N S K K K F G A D
Zebra Danio Brachydanio rerio NP_956242 439 48646 S69 D I Y P E S L S G K K K F G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 K92 T A V P V I K K I E H V G E V
Honey Bee Apis mellifera XP_393448 447 49774 S77 T A V K S P G S T S H Y L K K
Nematode Worm Caenorhab. elegans P34693 441 49885 T70 K E K V M Q Q T G M P E W A F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.8 95.2 N.A. 89.8 89.8 N.A. 91.5 30.8 82.8 65.3 N.A. 33.1 38.9 31.9 N.A.
Protein Similarity: 100 99.5 99.7 97.8 N.A. 94.5 94.8 N.A. 95.7 50.3 92.4 78.8 N.A. 48.7 59.7 49.6 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 100 0 93.3 20 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 0 100 20 N.A. 20 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 8 0 8 0 0 8 0 0 0 0 54 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 62 % D
% Glu: 0 8 0 62 8 0 0 0 0 8 0 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 62 8 0 8 % F
% Gly: 0 0 0 0 0 0 8 0 16 0 0 0 70 24 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % H
% Ile: 62 8 8 0 8 8 8 0 8 0 0 0 8 0 0 % I
% Lys: 8 0 8 8 0 0 8 8 62 70 70 8 0 8 8 % K
% Leu: 0 8 0 0 0 62 8 0 0 0 8 8 8 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 54 0 39 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 62 16 0 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 16 8 24 77 0 8 0 0 0 0 0 % S
% Thr: 16 0 0 0 0 0 0 8 8 0 0 0 0 0 8 % T
% Val: 0 0 16 8 8 0 0 8 0 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 62 8 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _