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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH8A1
All Species:
17.58
Human Site:
S340
Identified Species:
35.15
UniProt:
Q9H2A2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2A2
NP_072090.1
487
53401
S340
A
H
L
E
K
V
R
S
Y
V
K
R
A
L
A
Chimpanzee
Pan troglodytes
XP_001170111
490
53679
S343
A
H
L
E
K
V
R
S
Y
V
K
R
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001101362
515
55911
S368
A
H
L
E
K
V
R
S
Y
V
K
R
A
L
A
Dog
Lupus familis
XP_533415
487
53149
S340
A
H
L
E
K
V
R
S
Y
I
K
K
A
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH00
487
53645
S340
A
H
L
E
K
V
R
S
Y
V
L
K
A
Q
T
Rat
Rattus norvegicus
P13601
501
54541
K353
I
D
K
E
Q
H
A
K
I
L
D
L
I
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509667
487
53578
N340
E
H
L
Q
K
V
R
N
Y
V
R
K
A
R
D
Chicken
Gallus gallus
P27463
509
55791
K361
I
D
K
E
Q
F
Q
K
I
L
D
L
I
E
S
Frog
Xenopus laevis
Q6GNL7
902
99964
E760
A
H
L
D
K
L
I
E
Y
C
Q
T
G
V
K
Zebra Danio
Brachydanio rerio
Q66I21
487
53336
G340
E
H
L
Q
K
V
K
G
Y
I
T
L
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509203
506
55370
Y359
H
Y
E
K
V
K
S
Y
I
E
L
A
K
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YU0
501
54342
R348
Q
G
P
Q
V
D
K
R
Q
F
E
K
I
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
86
87.2
N.A.
89.9
38.3
N.A.
80.6
38.3
23.7
74.1
N.A.
N.A.
N.A.
49.4
N.A.
Protein Similarity:
100
94.2
89.1
95
N.A.
95.4
56.8
N.A.
90.3
55.5
36.5
87.6
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
73.3
6.6
N.A.
53.3
6.6
33.3
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
26.6
N.A.
80
33.3
60
73.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
9
0
0
0
0
9
59
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
17
0
9
0
9
0
0
0
0
17
0
0
0
9
% D
% Glu:
17
0
9
59
0
0
0
9
0
9
9
0
0
17
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% G
% His:
9
67
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
9
0
25
17
0
0
25
0
0
% I
% Lys:
0
0
17
9
67
9
17
17
0
0
34
34
9
9
9
% K
% Leu:
0
0
67
0
0
9
0
0
0
17
17
25
0
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
25
17
0
9
0
9
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
50
9
0
0
9
25
0
17
0
% R
% Ser:
0
0
0
0
0
0
9
42
0
0
0
0
0
0
34
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% T
% Val:
0
0
0
0
17
59
0
0
0
42
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
67
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _