KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
45.45
Human Site:
Y774
Identified Species:
76.92
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
Y774
T
L
S
V
I
R
D
Y
L
V
Q
K
L
Q
K
Chimpanzee
Pan troglodytes
XP_508805
941
107763
Y774
T
L
S
V
I
R
D
Y
L
V
Q
K
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
Y774
T
L
S
V
I
R
D
Y
L
V
Q
K
L
Q
K
Dog
Lupus familis
XP_546492
941
107605
Y774
T
L
S
V
I
R
D
Y
L
V
Q
K
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
Y774
T
L
S
I
I
R
D
Y
L
V
Q
K
L
Q
K
Rat
Rattus norvegicus
NP_001101608
878
101153
Y711
T
L
S
I
I
R
D
Y
L
V
Q
K
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
Y762
T
L
S
V
I
K
D
Y
L
V
N
K
L
Q
K
Frog
Xenopus laevis
NP_001088406
914
104616
Y747
T
L
S
V
I
R
E
Y
L
I
N
K
M
Q
K
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
Y759
S
L
S
V
I
K
D
Y
L
I
N
K
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
Y765
T
L
G
D
I
R
T
Y
L
N
S
V
L
L
T
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
Y755
T
I
S
S
V
R
D
Y
I
I
A
W
L
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
Y810
T
L
S
V
I
K
D
Y
I
A
R
K
L
E
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
L780
P
I
I
V
L
Q
T
L
A
K
N
P
C
L
T
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
I876
H
F
G
L
I
Q
D
I
I
I
D
H
V
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
73.3
60
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
N.A.
46.6
80
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
60
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
93.3
N.A.
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
79
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
15
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
15
8
15
86
0
0
8
22
29
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
22
0
0
0
8
0
72
0
8
65
% K
% Leu:
0
79
0
8
8
0
0
8
72
0
0
0
79
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
29
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
0
0
43
0
0
58
8
% Q
% Arg:
0
0
0
0
0
65
0
0
0
0
8
0
0
8
8
% R
% Ser:
8
0
79
8
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
79
0
0
0
0
0
15
0
0
0
0
0
0
0
22
% T
% Val:
0
0
0
65
8
0
0
0
0
50
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _